What are the symptoms of pancreatic cancer?

Written by Yan Chun
Oncology
Updated on February 01, 2025
00:00
00:00

Pancreatic cancer is a malignant tumor of the digestive system and its incidence has been increasing year by year. The symptoms of pancreatic cancer patients mainly include the following clinically: 1. Abdominal pain, which is a common manifestation in pancreatic cancer patients. It appears as intermittent pain in the early stages and as persistent severe abdominal pain in the middle and late stages. 2. Jaundice, especially common in patients with cancer of the head of the pancreas, tends to appear early. This jaundice is due to the compression of the bile duct by the tumor, often presenting as obstructive jaundice. Patients may also experience dark tea-colored urine and pale clay-colored stools. Additionally, pancreatic cancer patients may also experience symptoms like weight loss, fatigue, fever, and when the cancer metastasizes to other organs, symptoms related to the metastases may appear.

Other Voices

doctor image
home-news-image
Written by Yan Chun
Oncology
1min 2sec home-news-image

What are the signs of pancreatic cancer?

Pancreatic cancer is a type of malignant tumor of the digestive tract that is difficult to detect in its early stages. The signs of pancreatic cancer mainly include the following: First, among people with diabetes, if there is a sudden occurrence of uncontrollable blood sugar levels, unexplained general fatigue, abdominal pain, decreased appetite, or even jaundice, one should highly suspect the possibility of pancreatic cancer. Second, individuals with a family history of cancer who recently experience unexplained symptoms related to the digestive tract should also be alert to the possibility of pancreatic cancer. Third, some patients may experience unexplained rapid weight loss accompanied by significant jaundice, which should also be considered as potentially indicating pancreatic cancer.

doctor image
home-news-image
Written by Cui Fang Bo
Oncology
47sec home-news-image

What are the abnormalities in blood indicators for pancreatic cancer?

Blood markers for pancreatic cancer often show multiple abnormalities. Pancreatic cancer itself can lead to an increase in related tumor markers. The two most common markers are carcinoembryonic antigen and carbohydrate antigen 19-9, especially carbohydrate antigen 19-9, which has a certain specificity. If pancreatic cancer progresses further, leading to compression of the biliary system, corresponding jaundice indicators can increase. This includes an increase in total bilirubin and direct bilirubin, as well as alkaline phosphatase and gamma-GTP. The most common metastasis site for pancreatic cancer is the liver, and after liver metastasis occurs, corresponding liver transaminases can increase.

doctor image
home-news-image
Written by Zhou Zi Hua
Oncology
39sec home-news-image

Reasons for the low resection rate of pancreatic cancer

The resection rate for pancreatic cancer is relatively low because the pancreas is located behind the peritoneum in a deep position. In the early stages of pancreatic cancer, there are often no specific clinical symptoms. Therefore, by the time pancreatic cancer is detected in patients, it is usually already in the advanced stages. The pancreas is surrounded by blood vessels and nerves. Therefore, if it is found in the late stage, the surgical difficulty is very high, making it difficult to remove surgically, which is why the surgical resection rate for pancreatic cancer is low.

doctor image
home-news-image
Written by Yan Chun
Oncology
1min 4sec home-news-image

Early symptoms and signs of pancreatic cancer

Pancreatic cancer is a malignant tumor of the digestive system and does not have a high clinical incidence rate. Early symptoms of pancreatic cancer are not typical; some patients experience abdominal pain, primarily a persistent episodic pain that may radiate to the shoulder and back. Additionally, early-stage pancreatic head cancer patients may exhibit jaundice, often caused by obstructive jaundice due to tumor compression. Besides this, patients may also have clay-colored stools or urine the color of strong tea. Beyond these symptoms, early-stage patients exhibit no other signs. When typical clinical manifestations occur, they are generally indicative of mid to late-stage pancreatic cancer. Precursors to pancreatic cancer include persistent hidden pain in the shoulder or a stiff pain in the back. This continuous pain, often caused by the invasion of the abdominal nervous plexus, results in radiating pain.

doctor image
home-news-image
Written by Liu Liang
Oncology
43sec home-news-image

Which test for pancreatic cancer is the most accurate?

Abdominal ultrasound and abdominal CT scans are the most commonly used imaging methods for diagnosing pancreatic cancer. Additionally, it is important to consider the patient's symptoms and blood tests for tumor markers, mainly IP antigen, CEA, and CA19-9. Confirming pancreatic cancer requires a biopsy to find cancer cells, which is the gold standard for diagnosis. Other tests can serve as screening and adjunct diagnostic tools. Confirmation requires a biopsy for pathological diagnosis or direct radical surgery followed by a postoperative pathological confirmation.