Reasons for the low resection rate of pancreatic cancer

Written by Zhou Zi Hua

Oncology

Updated on September 09, 2024

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The resection rate for pancreatic cancer is relatively low because the pancreas is located behind the peritoneum in a deep position. In the early stages of pancreatic cancer, there are often no specific clinical symptoms. Therefore, by the time pancreatic cancer is detected in patients, it is usually already in the advanced stages. The pancreas is surrounded by blood vessels and nerves. Therefore, if it is found in the late stage, the surgical difficulty is very high, making it difficult to remove surgically, which is why the surgical resection rate for pancreatic cancer is low.

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What are the symptoms of late-stage pancreatic cancer?

Some common symptoms of advanced pancreatic cancer include abdominal pain and upper abdominal pain, and it is even possible to feel an obvious lump in the abdomen. Jaundice is also a common symptom. Some patients may also experience nausea, vomiting, abdominal bloating, and abdominal pain, even ascites, which is a sensation of abdominal fullness. They are unable to eat, and eating can worsen the bloating. These clinical manifestations are accompanied by clearly noticeable abdominal pain. There are also symptoms associated with distant organ metastasis, such as when metastasis to the lungs can cause shortness of breath, coughing, and even hemoptysis. Some patients may experience extensive abdominal metastasis, which can even lead to intestinal obstruction and other clinical presentations.

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What department should pancreatic cancer patients see?

For the treatment of pancreatic cancer, if it is in the early stages and the surgeons assess that surgery is feasible, surgical treatment is the main approach. If surgery is not feasible according to the surgeon's assessment, or if the cancer is found at an advanced stage without the opportunity for surgery, then the treatment involves chemotherapy or some symptomatic supportive treatments. Therefore, patients at their first consultation should initially visit the Department of Hepatobiliary Surgery to see if surgery is possible, and then consult the Department of Oncology for further treatment steps, especially for patients who do not have the opportunity for surgery, who need to visit the Department of Oncology.

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What should be done if pancreatic cancer has not metastasized?

If pancreatic cancer has not metastasized, then it might be in an early stage. In this situation, consultation with a hepatobiliary surgeon is necessary for the surgeon to assess whether curative surgery can be performed. If the surgeon determines that curative surgery is feasible, this should be the preferred treatment method. Post-operatively, based on whether there are symptoms of recurrence or metastasis, such as vascular tumor thrombi or lymph node metastases, decisions concerning the necessity for adjuvant radiotherapy or chemotherapy should be made based on these high-risk factors for recurrence and metastasis.

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What are the precursors of pancreatic cancer?

Pancreatic cancer is a malignant tumor that occurs in the digestive system clinically. Due to the hidden location of the pancreas, early symptoms of pancreatic cancer are generally not obvious. When individuals with a family history of pancreatic cancer exhibit unexplained fatigue or abdominal discomfort, or rapidly progressive jaundice symptoms in a short period, and if patients also have diseases such as diabetes, the possibility of pancreatic cancer should be considered. An abdominal CT scan, MRI, and other radiological examinations should be completed quickly. For identified pancreatic space-occupying lesions, early biopsy through puncture or direct exploratory laparotomy should be performed as soon as possible for treatment.

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Five Early Symptoms of Pancreatic Cancer

The five major symptoms of early pancreatic cancer patients include abdominal pain, jaundice, abdominal distension, diarrhea, fatigue, and more, among which the occurrence of abdominal pain is higher. Many patients with early pancreatic cancer experience persistent and hidden abdominal pain without other clinical symptoms, which often leads to missed opportunities for early diagnosis; Secondly, jaundice is also a main manifestation of early pancreatic cancer, particularly in the head of the pancreas, mainly due to the tumor causing obstructive jaundice; Thirdly, abdominal distension, which is generally a mild distension and often does not significantly attract clinical attention; Fourthly, patients often feel a general fatigue, which is difficult to alleviate with ordinary treatment methods; Lastly, diarrhea, which is often due to abnormal secretion of digestive fluids caused by the pathology, leading to diarrhea.