What should be done if pancreatic cancer has not metastasized?

Written by Liu Liang
Oncology
Updated on September 25, 2024
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If pancreatic cancer has not metastasized, then it might be in an early stage. In this situation, consultation with a hepatobiliary surgeon is necessary for the surgeon to assess whether curative surgery can be performed. If the surgeon determines that curative surgery is feasible, this should be the preferred treatment method. Post-operatively, based on whether there are symptoms of recurrence or metastasis, such as vascular tumor thrombi or lymph node metastases, decisions concerning the necessity for adjuvant radiotherapy or chemotherapy should be made based on these high-risk factors for recurrence and metastasis.

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Written by Liu Liang
Oncology
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Is a pancreatic tumor the same as pancreatic cancer?

Pancreatic tumors include benign and malignant tumors of the pancreas. Common benign pancreatic tumors include insulinomas, which can cause hypoglycemia due to excessive insulin secretion. Other benign tumors of the pancreas include adenomas, lipomas, and fibromas, which are relatively rare clinically. Malignant tumors of the pancreas are commonly referred to as pancreatic cancer, which has a high degree of malignancy. Early-stage pancreatic cancer patients are primarily treated with surgery.

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Written by Liu Liang
Oncology
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How to screen for pancreatic cancer

Pancreatic cancer is a common malignant tumor of the digestive tract. Due to its high malignancy and rapid progression, it severely affects human health. So how should pancreatic cancer patients be screened? Generally, abdominal ultrasound examination is the primary screening method. Another method is the examination of tumor markers, mainly carcinoembryonic antigen (CEA) and CA19-9. CA19-9 is a tumor marker with relatively high specificity and sensitivity for the diagnosis of pancreatic cancer. Therefore, during physical examinations, we can draw blood to check these tumor markers. If there is a significant increase in CA19-9 or CEA, further examinations of the pancreas, such as ultrasound or CT of the pancreas, should be conducted to further investigate whether there is a tumor in the pancreas.

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Written by Liu Liang
Oncology
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What does pancreatic cancer ascites mean?

When pancreatic cancer causes ascites, particularly a large amount, we can collect the ascites to search for cancer cells. This generally indicates peritoneal metastasis, or metastasis above the liver which can also cause substantial ascites. In such cases, it typically signifies that the disease has progressed to a late stage, classified as stage IV. Patients in this category are unable to undergo surgery and their treatment primarily involves chemotherapy. If the patient's overall condition is good, chemotherapy can be chosen. If the patient's condition is relatively poor, targeted therapy or oral anti-angiogenesis medications may be selected to control the pancreatic cancer and manage the tumor. If the patient's condition is particularly poor, the approach involves placing a peritoneal drainage tube to remove the ascites and providing the best possible symptomatic supportive care.

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Written by Yan Chun
Oncology
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Will the routine blood test be abnormal for pancreatic cancer?

Pancreatic cancer is a malignant tumor of the digestive system. In the early stages, most pancreatic cancer patients generally have normal routine blood test indicators and show no abnormalities. This is because the early lesions are localized, without invasion or metastasis, and therefore have minimal impact on the overall body, not causing abnormalities in routine blood test indicators. As the disease progresses, patients in the middle and late stages of pancreatic cancer often exhibit abnormalities in routine blood test indicators, mainly manifested as abnormalities in hemoglobin levels. Patients experience mild, moderate, or severe anemia. Some patients may also have metastasis to the bone marrow, liver, spleen, etc. Clinically, there can also be a decrease in white blood cells and platelets. Due to the impact of pancreatic cancer lesions on liver function, there can also be abnormalities in coagulation function.

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Written by Liu Liang
Oncology
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How is pancreatic cancer diagnosed?

The most common symptoms of pancreatic cancer are pain in the upper abdomen and jaundice. During physical examination, a mass in the upper abdomen can be felt, which is a common symptom. When these symptoms appear, further abdominal ultrasound or CT scans should be performed, as these two are the most commonly used imaging methods for diagnosing pancreatic cancer. Additionally, pancreatic MRI or PET-CT can also help enhance the diagnostic accuracy for pancreatic cancer. MRCP and ERCP are also used to assess the bile ducts and to evaluate the feasibility of surgery. Blood tests for pancreatic cancer-related tumor markers, such as carcinoembryonic antigen (CEA) and CA19-9, are commonly performed, with CA19-9 being particularly sensitive and specific for the diagnosis of pancreatic cancer.