Common symptoms of duodenal bulb ulcers include stomach pain, bloating, belching, acid reflux, nausea, and vomiting. A gastroscopy can reveal defects in the duodenal mucosa, which can be diagnosed as duodenal ulcers. Drinking alcohol can irritate the gastric mucosa as well as the duodenal mucosa. If there is an ulcer in the duodenal bulb and alcohol is consumed, it can exacerbate the ulcer, causing the ulcerated area to enlarge and more severe symptoms to appear. Therefore, drinking alcohol can lead to the worsening of duodenal ulcers. Thus, individuals with gastric diseases or peptic ulcers must abstain from alcohol, as it can aggravate the existing condition. If a duodenal ulcer worsens, penetrating the serosal or basal layer, it may lead to perforation. In such cases, emergency surgery is required for treatment. Hence, it is crucial for those with duodenal ulcers to avoid alcohol.