Is duodenal ulcer bleeding a sign of cancerous change?

Written by Wu Hai Wu
Gastroenterology
Updated on October 19, 2024
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Duodenal ulcer bleeding does not indicate cancerous changes. The duodenal area is relatively thin, so once a duodenal ulcer occurs, it is more likely to lead to complications such as ulcer bleeding and perforation. If vomiting blood occurs with a duodenal ulcer, it indicates that the patient with the duodenal ulcer has a bleeding complication. In terms of treatment, it is first necessary to complete an endoscopic examination, which can include endoscopic hemostasis; secondly, proton pump inhibitors should be used to suppress the secretion of stomach acid and increase the pH level in the stomach; additionally, treatments that protect the stomach lining, such as aluminum hydroxide and magnesium carbonate, should be used. (Medication should be taken under the guidance of a physician.)

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Written by Wang Hui Jie
Gastroenterology
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The difference between gastric ulcers and duodenal ulcers.

The differences between gastric ulcers and duodenal ulcers, in terms of symptoms, include that gastric ulcers often manifest as burning pain, or dull pain, distention pain, etc., usually postprandial pain, occasionally with nighttime pain. If it occurs at the pyloric canal, it lacks typical symptoms, with intense pain likely occurring after eating, and poor drug efficacy, prone to vomiting and pyloric obstruction, perforation, and bleeding. Gastric ulcers have a minor possibility of becoming cancerous. Duodenal ulcer pain is mostly located in the upper abdomen, characterized by hunger pain and midnight pain. Abdominal pain generally eases after eating or taking some antacid medications. For ulcers occurring behind the bulb, nighttime pain and a radiating pain in the back are more common. However, the effectiveness of medication is relatively poor, and it is prone to bleeding. Duodenal ulcers are more likely to lead to perforation and pyloric obstruction, but generally do not become cancerous.

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Written by Wang Li Wei
Gastroenterology
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How to examine the duodenum?

For some diseases of the duodenum, such as inflammation, ulcers, polyps, and tumors of the duodenum, the main examination method is gastroscopy. Gastroscopy can clearly and accurately identify the nature and location of the specific lesions. Additionally, by taking biopsies for pathology, it can specifically determine the benign or malignant nature of the disease, which is very helpful for subsequent treatment plans.

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Written by Si Li Li
Gastroenterology
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What will happen if you drink alcohol with a duodenal bulb ulcer?

Common symptoms of duodenal bulb ulcers include stomach pain, bloating, belching, acid reflux, nausea, and vomiting. A gastroscopy can reveal defects in the duodenal mucosa, which can be diagnosed as duodenal ulcers. Drinking alcohol can irritate the gastric mucosa as well as the duodenal mucosa. If there is an ulcer in the duodenal bulb and alcohol is consumed, it can exacerbate the ulcer, causing the ulcerated area to enlarge and more severe symptoms to appear. Therefore, drinking alcohol can lead to the worsening of duodenal ulcers. Thus, individuals with gastric diseases or peptic ulcers must abstain from alcohol, as it can aggravate the existing condition. If a duodenal ulcer worsens, penetrating the serosal or basal layer, it may lead to perforation. In such cases, emergency surgery is required for treatment. Hence, it is crucial for those with duodenal ulcers to avoid alcohol.

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Written by Jiang Guo Ming
Gastroenterology
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Where does a duodenal ulcer hurt?

Firstly, the common sites for duodenal ulcers are the anterior and posterior walls posterior to the bulb, as well as the area behind the duodenal bulb itself. The pain symptoms typically show a pattern. For example, the pain occurs in recurrent, cyclical episodes related to eating, manifesting as sporadic abdominal pain about 2cm above the right side of the belly button, more pronounced on an empty stomach, and alleviating after meals. Sometimes, there is also pain during the night. If the ulcer is located behind the duodenal bulb, it often causes back pain. The main cause is usually an infection with Helicobacter pylori, and eradication therapy can generally cure the condition.

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Written by Wu Hai Wu
Gastroenterology
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Is hot compress effective for duodenal ulcer?

Patients with duodenal ulcers may achieve some effects through hot compresses, but hot compresses cannot truly effectively treat duodenal ulcers. To effectively treat duodenal ulcers, it is first necessary to detect the presence of Helicobacter pylori infection through the carbon-13 breath test or carbon-14 breath test. If the Helicobacter pylori infection is positive, it is necessary to eradicate Helicobacter pylori using a quadruple therapy containing bismuth. Subsequently, it is important to use proton pump inhibitors or H2 receptor antagonists to inhibit gastric acid secretion, and medications like aluminum magnesium carbonate to protect the gastric mucosa. (The use of medications should be under the guidance of a physician.)