How is endometrial cancer diagnosed?

Written by Liu Jian Wei
Obstetrics and Gynecology
Updated on September 12, 2024
00:00
00:00

In the clinical setting, when endometrial cancer is suspected, further pathological examination is required. Generally, endometrial tissue can be obtained through fractional curettage or hysteroscopic endometrial biopsy. The acquired endometrium is then subject to a pathological examination, observing the morphology of the endometrial cells under a microscope. If cancer cells are detected, a diagnosis of endometrial cancer can be made. Therefore, the confirmation of endometrial cancer in clinical practice must be based on pathological examination.

Other Voices

doctor image
home-news-image
Written by Li Shun Hua
Obstetrics and Gynecology
52sec home-news-image

Is endometrial hyperplasia the same as cancer?

Endometrial hyperplasia is not cancer; it is caused by a prolonged absence of ovulation, which means there is no secretion of progesterone. This prevents the proliferative phase endometrium from transforming into the secretory phase, leading to hyperplasia. If the hyperplasia persists over an extended period, it may lead to precancerous changes in the endometrium, and in severe cases, it can cause endometrial cancer. Therefore, it is essential to treat endometrial hyperplasia with progesterone, which can transform the endometrium and allow it to shed completely, altering its condition and restoring it to normal. As long as there is ovulation, there is the production of progesterone, so promoting ovulation is crucial.

doctor image
home-news-image
Written by Liu Jian Wei
Obstetrics and Gynecology
55sec home-news-image

How to perform surgery for endometrial cancer

Surgical treatment for endometrial cancer needs to be determined based on the specific stage and type of the cancer, as well as the size of the lesions. If the lesions are small and the cancer is in an early stage, a complete hysterectomy including the removal of both fallopian tubes and ovaries can be performed. Intraoperative pathology assessment of the endometrium is also necessary to determine the specific pathological type. If it is a special type of endometrial cancer, it is also necessary to clear the pelvic lymph nodes. If the endometrial cancer is at a later stage and the lesions are larger, then in addition to the removal of the uterus and both fallopian tubes and ovaries, it is also necessary to clear the lymph nodes around the abdominal aorta in the pelvis.

doctor image
home-news-image
Written by Shen Li Wen
Obstetrics and Gynecology
44sec home-news-image

Early symptoms of endometrial cancer

When endometrial cancer occurs in women, it first manifests as abnormal proliferation of the endometrium, increased endometrial surface area, and increased secretions, which can increase the pressure inside the uterine cavity, leading to lower abdominal pain in women. Most women can tolerate this pain, but it tends to worsen during vigorous activities or sexual intercourse. Vaginal discharge may become watery and increase. Additionally, some women may experience increased menstrual flow or irregular vaginal bleeding. Over time, this can lead to blood loss anemia in women, manifesting as dizziness, fatigue, and changes in appetite.

doctor image
home-news-image
Written by Xu Xiao Ming
Obstetrics and Gynecology
53sec home-news-image

Stage IB endometrial cancer treatment

Endometrial carcinoma Stage IB refers to tumors localized to the body of the uterus, where tumor infiltration is less than half of the myometrium. Surgical treatment is feasible for this stage and involves a slightly extensive total hysterectomy coupled with bilateral adnexectomy. During the surgery, a frozen section pathology test should be conducted. If the pathology report from the frozen section indicates special types of endometrial-like cancer, including papillary serous adenocarcinoma, clear cell carcinoma, squamous cell carcinoma, carcinosarcoma, and undifferentiated carcinoma, additional procedures are required. Moreover, if enlarged para-aortic or common iliac lymph nodes are palpated during the surgery, lymphadenectomy of the pelvic and para-aortic lymph nodes should be performed.

doctor image
home-news-image
Written by Du Rui Xia
Obstetrics
59sec home-news-image

Is surgery necessary for endometrial cancer?

For endometrial cancer, surgery is generally recommended as the first choice, because early-stage endometrial cancer can largely be cured through surgical treatment. Besides surgery, other options include medication, radiation therapy, and chemotherapy, which are used for mid to late stages or in conjunction with surgery in early stages. When treating endometrial cancer, the treatment method should be chosen based on the specific condition and stage of the patient. In early-stage endometrial cancer, surgery is the preferred treatment. Therefore, aside from surgical treatment, patients should choose medication, radiation therapy, or chemotherapy based on their specific conditions.