What is early-stage gastric cancer?

Written by Liu Liang
Oncology
Updated on April 05, 2025
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In the early stages of gastric cancer, the tumor is confined to the mucosa or submucosa, regardless of whether there is regional lymph node metastasis or not; this is still classified as early-stage gastric cancer. The treatment for early-stage gastric cancer primarily involves curative surgery, which is the first option unless the patient is of advanced age or has severe underlying diseases that prevent tolerance of surgical treatment. Excluding these cases, surgical treatment is generally the first choice. Furthermore, the outcome of surgical treatment for patients with early-stage gastric cancer is generally quite positive, with a five-year survival rate typically exceeding 80%.

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Written by Liu Liang
Oncology
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Can late-stage gastric cancer be treated?

Patients with late-stage gastric cancer generally may not have the opportunity for curative surgery, which is mainly suitable for early-stage gastric cancer patients. For late-stage gastric cancer patients, the treatment plan should be chosen based on the specific condition of the patient. If the patient's general condition is relatively good, chemotherapy can be an option. The type of chemotherapy, whether intravenous combination chemotherapy or oral drugs like tegafur capsules or capecitabine, which generally have milder reactions, depends on the patient's condition. Additionally, late-stage gastric cancer patients can try molecular targeted therapy, such as anti-angiogenesis drugs like apatinib, etc. Therefore, treatment options should be selected based on specific circumstances. The use of medications should be conducted under the guidance of a doctor.

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Written by Zhou Zi Hua
Oncology
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What are the symptoms of stomach cancer?

Gastric cancer can cause pain in the upper abdomen. If the condition gradually worsens, it can manifest as persistent pain, postprandial fullness and vomiting, belching, and lack of appetite; upper gastrointestinal bleeding, manifesting as vomiting blood, blood in the stool, and black stools; there can also be difficulty swallowing, weight loss and anemia. If bone metastasis occurs, it can manifest as bone pain and pain in the lower back. If a large amount of ascites appears, it can lead to abdominal distension, with shifting dullness detectable on percussion. If liver metastasis occurs, it can manifest as jaundice, and enlargement of the supraclavicular lymph nodes can also occur.

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Written by Ren Zheng Xin
Gastroenterology
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Is stomach cancer nauseating?

If gastric cancer is complicated by pyloric obstruction, symptoms such as nausea and vomiting may occur. 80% of early gastric cancer does not show obvious symptoms; some people may experience indigestion, as well as anemia, anorexia, and fatigue. If cardia cancer involves the lower part of the esophagus, it can cause difficulty in swallowing, while ulcerative gastric cancer bleeding can lead to vomiting blood or black stools. If gastric cancer metastasizes to the liver, it can cause pain in the upper right abdomen, jaundice, or fever, and if it involves the pancreas, it may cause radiating back pain. If there are long-term symptoms such as indigestion, physical weakness, and loss of appetite, it is advisable to actively visit the department of gastroenterology for a gastroscopy examination.

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Written by Zhou Zi Hua
Oncology
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Early symptoms of gastric cancer

The symptoms of early gastric cancer are nonspecific and similar to those of chronic gastritis, gastric ulcers, gastroparesis, and other benign diseases, making it difficult to distinguish. Screening data shows that 40%-60% of patients with early gastric cancer are asymptomatic. The symptoms of early gastric cancer primarily include pain or discomfort in the upper abdomen, loss of appetite, fatigue, vomiting, hematemesis, blood in stools, melena, and difficulty swallowing. Discomfort in the upper abdomen is the most common symptom, followed by pain beneath the sternum. Generally, early gastric cancer does not present specific physical signs, though tenderness in the upper abdomen is relatively common, and some patients may exhibit signs of anemia.

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Written by Wang Hui Jie
Gastroenterology
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Early symptoms of gastric cancer

The early symptoms of gastric cancer are not specific or characteristic in clinical presentations, and there are no specific signs either. It can also be said that there are no symptoms or signs at all. Some patients may be diagnosed with gastric cancer after presenting with symptoms of bleeding, such as vomiting blood, blood in stool, or black stools. Therefore, it is recommended for individuals over 40 years old to consider undergoing gastroscopy, especially if they experience discomfort or pain in the upper abdomen, weight loss, or have a history of poor gastric mucosa conditions seen in previous gastroscopies, including atrophy, intestinal metaplasia, or ulcers, as well as a history of testing positive for Helicobacter pylori. Regular follow-up gastroscopies are advised under these circumstances.