Systemic lupus erythematosus has several symptoms, including:

Written by Liu Li Ning
Rheumatology
Updated on May 14, 2025
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Common manifestations of lupus include facial butterfly rash, discoid rash, photosensitivity, joint pain or arthritis, mental symptoms, recurrent oral ulcers, hair loss, foamy urine, etc.

Patients with mesenteric vasculitis as the initial symptom mainly complain of abdominal pain and bloating.

If the hematological system is the initial symptom, the main complaint is usually fatigue.

If the patient presents with a seizure as the initial symptom, the main manifestation is limb convulsions.

The heterogeneity of lupus is strong, and different patients can exhibit completely different clinical manifestations.

Other Voices

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Written by Zhang Lin
Rheumatology and Immunology Nephrology
1min 19sec home-news-image

What foods are good for lupus erythematosus?

The diet for patients with lupus erythematosus varies from person to person. Generally, the ideal food for lupus patients should have the following characteristics: an appropriate amount of high-quality protein, low fat, low salt, low sugar, and rich in vitamins and calcium. Since many lupus patients often have significant kidney damage, proteins are frequently lost in large amounts through the urine, causing hypoalbuminemia and edema. The supplementation of protein should primarily consist of high-quality animal proteins, such as milk, eggs, and lean meats. However, protein intake should also be appropriate and not excessive. Excessive intake can not only lead to incomplete absorption by the patient, increasing the burden on the gastrointestinal tract, but also increase the excretion of nitrogenous compounds in the body, further burdening the kidneys. Lupus patients should avoid or minimize consumption of foods that can enhance photosensitivity, such as figs, rapeseed, cilantro, and celery. If consumed, they should avoid sun exposure afterwards. Mushrooms, smoked foods, and certain food dyes can also trigger lupus and should be avoided or minimized in the diet.

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Written by Zhang Lin
Rheumatology and Immunology Nephrology
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Can people with lupus eat mangoes?

For patients with lupus erythematosus, we recommend caution in consuming mangoes. Mangoes are among the fruits that commonly cause allergies. After allergic reactions, most people develop rashes, and skin redness is a symptom of lupus erythematosus. If an allergy is triggered, it can worsen the redness and may also be confused with the rash associated with lupus patients. We can eat some grapes, as grapes are a nourishing food that promotes health and longevity. We can also eat some watermelons, which are rich in water and act as a natural nutrient solution, containing various nutrients. However, the intake of food should not be excessive.

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Written by Liu Li Ning
Rheumatology
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What happens if someone with lupus occasionally drinks alcohol?

Systemic lupus erythematosus (SLE) is an autoimmune disease that can affect multiple systems and organs throughout the body and is more commonly seen in women, particularly during their childbearing years. Clinically, it is mainly characterized by fever, rash, joint pain, oral ulcers, and hair loss. In terms of diet, it is recommended to eat light and avoid spicy and irritating foods. It is crucial to strictly abstain from smoking and drinking, avoid excessive fatigue, and direct sun exposure. Importantly, patients should strictly follow medical advice regarding medication and have regular check-ups.

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Written by Zhang Lin
Rheumatology and Immunology Nephrology
1min 6sec home-news-image

What should I do if I have a fever with lupus erythematosus?

When patients with lupus experience fever, the fundamental approach is the use of ample steroids or other immunosuppressive drugs for treatment, which generally can quickly normalize body temperature. However, some patients may also experience fever during steroid use, possibly due to the steroids reducing immune function and inducing a bacterial infection. At this point, it is necessary to find evidence of infection and promptly treat with adequate sensitive antibiotics. Then, there will certainly be questions about why patients with lupus who have a fever cannot use antibacterial drugs or antipyretics. This is because fever in lupus patients is often an important indicator of disease activity. During acute phases, the fever is typically high, not caused by external infections, thus antibacterial drugs are ineffective. Using antipyretics can temporarily normalize body temperature, but once the effect of the medication wears off, the high fever may recur. Patients with lupus should not casually use medications. If medication is needed, it should be used under the guidance of a doctor.

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Written by Zhang Lin
Rheumatology and Immunology Nephrology
56sec home-news-image

Lupus is what disease?

Lupus erythematosus, also known as systemic lupus erythematosus, is a chronic autoimmune disease involving multiple systems and organs. Patients' serum contains various autoantibodies, with the main pathological changes being inflammatory reactions and vascular abnormalities. Most patients exhibit butterfly-shaped erythema on the bridge of the nose and cheeks, which is the most characteristic manifestation of lupus erythematosus. The clinical presentations of systemic lupus erythematosus are diverse, generally characterized by the "four multiples": involvement of multiple systems, multiple organs, multiple autoantibodies, and a higher prevalence among women of childbearing age. Without proper and effective treatment, the mortality rate is high, with the main causes of death being infections, renal failure, and damage to the central nervous system.