Do the rashes caused by lupus itch?

Written by Liu Li Ning
Rheumatology
Updated on January 23, 2025
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The erythema triggered by lupus erythematosus may or may not be itchy, varying from person to person, with each individual's condition not being entirely the same. The erythema caused by systemic lupus erythematosus also presents very differently clinically, with the typical manifestation being a butterfly-shaped erythema on the face. Other common forms include discoid erythema, reticular purpura, polymorphic rash, periungual erythema, and more. The specific pathogenic mechanism is currently unclear, and in some patients, the condition is caused by photosensitivity. After treatment, the erythema cannot completely disappear in a significant number of patients, leaving some pigment deposition. If only the skin is affected, treatment can involve the topical use of tacrolimus ointment or the oral intake of immunomodulators like hydroxychloroquine, and if necessary, oral corticosteroids may be administered.

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For lupus, register under the department of Rheumatology.

Patients with lupus should visit the Department of Rheumatology and Immunology, as lupus is a clinically complex autoimmune disease. Many people think that lupus is a skin disease, but this is not the case. Lupus is a rheumatic and immunological disease, belonging to the category of rheumatic immunological diseases, and is an uncommon autoimmune disease.

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Can lupus patients get pregnant?

Patients with lupus can conceive normally, but it is not recommended to become pregnant. This is because patients with lupus who become pregnant are prone to miscarriage, preterm birth, stillbirth, and poor fetal development in the uterus, especially in patients who are positive for antiphospholipid antibodies. Pregnancy can also aggravate the disease or cause a relapse in lupus patients, and even if the disease is stable, there are cases where the condition worsens during pregnancy or after childbirth. Therefore, it is not recommended for patients with active systemic lupus erythematosus to become pregnant. If the condition has been stable for more than a year after treatment and the patient has been off medication for at least 6 months, then pregnancy can be considered. However, it is important to note that dexamethasone, immunosuppressants, and Tripterygium wilfordii tablets have side effects on the fetus and should be avoided.

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Written by Yan Xin Liang
Pediatrics
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Symptoms of childhood lupus

Childhood systemic lupus erythematosus generally presents similarly to adults. It is a relatively common systemic autoimmune disease, more commonly seen in girls than boys. It involves multiple autoantibodies primarily including antinuclear antibodies and widespread small arteriole pathology, affecting multiple systems. Clinically, it can manifest with fever, skin lesions, such as butterfly rash on the face, as well as damage to the joints, kidneys, liver, heart, serous membranes, and a reduction in all blood cells. Generally, the ratio of females to males ranges from about 6:1 to 9:1. The prognosis of this disease is generally poor.

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Written by Liu Li Ning
Rheumatology
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How long will the skin itch in the early stages of lupus erythematosus?

The duration of itching in the early stages of lupus erythematosus is not fixed. It is not certain that early-stage lupus erythematosus will cause itching. Some patients may experience itching, which can subside on its own, but it tends to recur. Additionally, some patients may have itching due to allergies, which can result in rashes accompanied by itching. It is possible to check immunoglobulin E to see if there are any allergic factors present. If allergies are involved, treatment can include antihistamines or corticosteroids, or topical calamine lotion can be used to relieve symptoms. Besides affecting the skin, early-stage lupus erythematosus can also cause symptoms such as oral ulcers and arthritis in many patients.

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Written by Liu Li Ning
Rheumatology
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What does the early rash of lupus look like?

The early characteristic rash of lupus erythematosus is typically a butterfly-shaped rash on the face. Other common presentations include palm and periungual erythema, discoid rash, nodular erythema, and livedo reticularis. If the rash is not notably itchy, it generally indicates lupus erythematosus. If there is significant itching, it may suggest the possibility of an allergic factor active in the disease. After immunosuppression, itchy rashes should be monitored for possible fungal infections. The specific pathogenesis of systemic lupus erythematosus is still unclear. If a patient exhibits the typical butterfly-shaped rash on the face, systemic lupus erythematosus should be highly suspected. Testing for antinuclear antibodies, and specifically for anti-Sm and double-stranded DNA antibodies, which represent a variety of autoantibodies, can diagnose systemic lupus erythematosus.