Symptoms of lupus cerebritis

Written by Liu Li Ning
Rheumatology
Updated on May 02, 2025
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Symptoms of lupus cerebritis can range from mild to severe. Mild symptoms include migraines, personality changes, memory loss, or mild cognitive impairment. Severe cases may present with cerebrovascular accidents, coma, status epilepticus, and other central nervous system symptoms, including aseptic meningitis, cerebrovascular disease, demyelinating syndrome, headaches, movement disorders, spinal cord disease, epileptic seizures, acute mental confusion, anxiety, cognitive impairment, mood disturbances, and psychiatric disorders. Peripheral nervous system manifestations include Guillain-Barre syndrome, autonomic dysfunction, mononeuritis, myasthenia gravis, cranial nerve disorders, nerve plexus disorders, and polyneuritis.

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Written by Liu Li Ning
Rheumatology
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Where does lupus erythematosus generally appear?

Lupus erythematosus can appear on various parts of the body. The most typical rash is the butterfly rash on the face, but it can also appear on other parts, such as discoid lupus, annular erythema, periungual erythema, and livedo reticularis. Additionally, systemic lupus erythematosus affects not only the skin and mucosa but can also involve the lungs, kidneys, heart, central nervous system, and other systems. Common manifestations include lupus nephritis and lupus pneumonia. The precise pathogenesis of systemic lupus erythematosus is still unclear. If the damage is confined to the skin and mucosa, immunomodulators such as hydroxychloroquine can be used for treatment. If important organs are involved, it generally requires long-term maintenance treatment with corticosteroids combined with immunosuppressants to control the progression of the disease.

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Written by Liu Li Ning
Rheumatology
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Symptoms of lupus cerebritis

Symptoms of lupus cerebritis can range from mild to severe. Mild symptoms include migraines, personality changes, memory loss, or mild cognitive impairment. Severe cases may present with cerebrovascular accidents, coma, status epilepticus, and other central nervous system symptoms, including aseptic meningitis, cerebrovascular disease, demyelinating syndrome, headaches, movement disorders, spinal cord disease, epileptic seizures, acute mental confusion, anxiety, cognitive impairment, mood disturbances, and psychiatric disorders. Peripheral nervous system manifestations include Guillain-Barre syndrome, autonomic dysfunction, mononeuritis, myasthenia gravis, cranial nerve disorders, nerve plexus disorders, and polyneuritis.

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Written by Liu Li Ning
Rheumatology
55sec home-news-image

Does lupus erythematosus transmit through living and eating together?

Lupus erythematosus is not contagious through sharing meals or living together. It is an autoimmune disease, not an infectious one, hence it cannot be transmitted to others by living or eating together. The exact mechanism of lupus is currently unclear, but it may be related to various factors such as sex hormones, genetics, infections, and physical and chemical factors, and it is more commonly seen in females. Clinically common symptoms include fever, rash, joint pain, oral ulcers, hair loss, etc. The clinical manifestations vary depending on the affected target organ. If lupus nephritis occurs, symptoms such as edema can appear. If the lungs are involved, it can promote pulmonary interstitial fibrosis, and in severe cases, patients may experience chest tightness, shortness of breath, and breathing difficulties.

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Written by Zhang Lin
Rheumatology and Immunology Nephrology
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What should I do if I have a fever with lupus erythematosus?

When patients with lupus experience fever, the fundamental approach is the use of ample steroids or other immunosuppressive drugs for treatment, which generally can quickly normalize body temperature. However, some patients may also experience fever during steroid use, possibly due to the steroids reducing immune function and inducing a bacterial infection. At this point, it is necessary to find evidence of infection and promptly treat with adequate sensitive antibiotics. Then, there will certainly be questions about why patients with lupus who have a fever cannot use antibacterial drugs or antipyretics. This is because fever in lupus patients is often an important indicator of disease activity. During acute phases, the fever is typically high, not caused by external infections, thus antibacterial drugs are ineffective. Using antipyretics can temporarily normalize body temperature, but once the effect of the medication wears off, the high fever may recur. Patients with lupus should not casually use medications. If medication is needed, it should be used under the guidance of a doctor.

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Written by Liu Li Ning
Rheumatology
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How long will the skin itch in the early stages of lupus erythematosus?

The duration of itching in the early stages of lupus erythematosus is not fixed. It is not certain that early-stage lupus erythematosus will cause itching. Some patients may experience itching, which can subside on its own, but it tends to recur. Additionally, some patients may have itching due to allergies, which can result in rashes accompanied by itching. It is possible to check immunoglobulin E to see if there are any allergic factors present. If allergies are involved, treatment can include antihistamines or corticosteroids, or topical calamine lotion can be used to relieve symptoms. Besides affecting the skin, early-stage lupus erythematosus can also cause symptoms such as oral ulcers and arthritis in many patients.