Symptoms of lupus cerebritis

Written by Liu Li Ning
Rheumatology
Updated on May 02, 2025
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Symptoms of lupus cerebritis can range from mild to severe. Mild symptoms include migraines, personality changes, memory loss, or mild cognitive impairment. Severe cases may present with cerebrovascular accidents, coma, status epilepticus, and other central nervous system symptoms, including aseptic meningitis, cerebrovascular disease, demyelinating syndrome, headaches, movement disorders, spinal cord disease, epileptic seizures, acute mental confusion, anxiety, cognitive impairment, mood disturbances, and psychiatric disorders. Peripheral nervous system manifestations include Guillain-Barre syndrome, autonomic dysfunction, mononeuritis, myasthenia gravis, cranial nerve disorders, nerve plexus disorders, and polyneuritis.

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Written by Zhang Lin
Rheumatology and Immunology Nephrology
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Can lupus patients get pregnant?

Patients with lupus can conceive normally, but it is not recommended to become pregnant. This is because patients with lupus who become pregnant are prone to miscarriage, preterm birth, stillbirth, and poor fetal development in the uterus, especially in patients who are positive for antiphospholipid antibodies. Pregnancy can also aggravate the disease or cause a relapse in lupus patients, and even if the disease is stable, there are cases where the condition worsens during pregnancy or after childbirth. Therefore, it is not recommended for patients with active systemic lupus erythematosus to become pregnant. If the condition has been stable for more than a year after treatment and the patient has been off medication for at least 6 months, then pregnancy can be considered. However, it is important to note that dexamethasone, immunosuppressants, and Tripterygium wilfordii tablets have side effects on the fetus and should be avoided.

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Written by Liu Li Ning
Rheumatology
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What should I do about lupus erythematosus?

Lupus erythematosus requires early and formal treatment to stabilize the condition. For mild cutaneous lupus erythematosus, topical immunosuppressants, such as tacrolimus ointment, and immunomodulators, such as hydroxychloroquine, can be used. Low-dose corticosteroids may be necessary for combination therapy. Systemic lupus erythematosus generally requires corticosteroids as the basis of treatment, combined with one or several immunosuppressants to effectively control the disease. Systemic lupus erythematosus often involves multiple organs, with the kidneys, hematological system, and lungs being the most common. Therefore, it is necessary to use corticosteroids in combination with immunosuppressants to control the progression of the disease, as using only immunomodulators is often insufficient.

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Written by Zhang Lin
Rheumatology and Immunology Nephrology
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What foods are good for lupus erythematosus?

The diet for patients with lupus erythematosus varies from person to person. Generally, the ideal food for lupus patients should have the following characteristics: an appropriate amount of high-quality protein, low fat, low salt, low sugar, and rich in vitamins and calcium. Since many lupus patients often have significant kidney damage, proteins are frequently lost in large amounts through the urine, causing hypoalbuminemia and edema. The supplementation of protein should primarily consist of high-quality animal proteins, such as milk, eggs, and lean meats. However, protein intake should also be appropriate and not excessive. Excessive intake can not only lead to incomplete absorption by the patient, increasing the burden on the gastrointestinal tract, but also increase the excretion of nitrogenous compounds in the body, further burdening the kidneys. Lupus patients should avoid or minimize consumption of foods that can enhance photosensitivity, such as figs, rapeseed, cilantro, and celery. If consumed, they should avoid sun exposure afterwards. Mushrooms, smoked foods, and certain food dyes can also trigger lupus and should be avoided or minimized in the diet.

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Written by Zhang Lin
Rheumatology and Immunology Nephrology
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Can lupus be treated without steroids?

Hormones are currently the first choice of drugs for treating lupus erythematosus, and there are no other drugs that can replace them temporarily, so we still recommend using hormones for treatment. Hormones can quickly and effectively suppress the immune response, reducing the damage to the patient's body from the inflammatory substances released during the immune response. This kind of immune-suppressive and anti-inflammatory action is a protective therapeutic effect on the body. Although long-term use of large doses of hormones has certain side effects, it can quickly block the development of the disease and alleviate the condition. The function of hormones cannot be replaced by any other drug at present, so, no matter what stage the lupus erythematosus patients are in and regardless of the type of damage, hormones are the first choice of drugs. Hormones have many side effects, therefore, we need to use hormone drugs for treatment rationally and standardized under the guidance of a doctor, and should not take them arbitrarily to avoid serious consequences.

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Written by Liu Li Ning
Rheumatology
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What is lupus and is it serious?

Lupus erythematosus is an autoimmune disease, which can be very severe in some cases and mild in others. For example, cutaneous lupus erythematosus generally does not involve major organs and usually presents with mild symptoms, primarily affecting the skin and mucous membranes. However, systemic lupus erythematosus can affect significant organs like the kidneys and heart in many patients, often leading to severe medical conditions. Especially, patients with rapidly progressive glomerulonephritis and those with coronary atherosclerotic heart disease tend to have a higher mortality rate. If systemic lupus erythematosus is diagnosed, it is crucial to receive standardized treatment early. Typically, treatment involves long-term maintenance with corticosteroids and immunosuppressants to control the progression of the disease and reduce the likelihood of mortality.