Are all lymphomas malignant?

Written by Liu Liang

Oncology

Updated on September 29, 2024

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Tumors can be benign or malignant; malignant tumors are commonly referred to as cancer. Lymphoma, because it originates from lymph nodes or tissues or organs outside the lymph nodes, is a type of malignant tumor, and thus it is called lymphoma. All lymphomas are malignant; there are no benign lymphomas. However, based on specific pathological types, lymphomas are classified into two main categories: non-Hodgkin lymphoma and Hodgkin lymphoma, but all lymphomas are malignant.

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Written by Liu Liang

Oncology

46sec

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Is lymphoma a cancer?

Cancer actually refers to malignant tumors. Malignant tumors are named differently based on their site of origin. For example, those originating from epithelial tissue are called carcinomas, such as lung cancer, liver cancer, colon cancer, etc. Lymphoma refers to a malignant tumor originating from lymph nodes or tissues or organs outside the lymph nodes, which we call lymphoma. There are also some malignant tumors originating from mesenchymal tissue, which we call sarcomas. Therefore, lymphoma is also a malignant tumor and is considered a type of cancer.

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Written by Zhou Zi Hua

Oncology

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Which department do you go to for lymphoma?

If a lump is found on the neck and lymphoma is suspected, the first step is to consult with the head and neck surgery department. The lymphoma lesion will be surgically removed by the department, and then sent for a pathological examination. If lymphoma is confirmed, the next steps involve treatment by the oncology department, hematology department, or radiation therapy department.

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Written by Peng Li Bo

Oncology

40sec

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What is lymphoma Ki-67?

Lymphoma Ki67, also known as the proliferation index, is one of the indicators in immunohistochemistry performed after the pathological diagnosis of lymphoma. If this proliferation index is higher, it indicates that the activity of the tumor is stronger, and its proliferation is more active, thus the tumor should be given sufficient attention. Of course, active treatment should be pursued. Therefore, Ki67 reflects the activity of a tumor; if the index is very high, greater than 90%, it sometimes implies that the tumor can grow very rapidly, or not only grows significantly but might also spread to many places.

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Written by Zhang Xiao Le

Hematology

48sec

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How to rule out lymphoma in children

Lymphoma is a malignant tumor originating from the lymphatic system. The main clinical manifestation is painless lymph node enlargement, which can occur in superficial lymph nodes such as in the neck, armpits, or groin, as well as deeper lymph nodes in the mediastinum or abdominal cavity. In pediatric patients with lymphoma, a significant number also present with abdominal pain, intestinal obstruction, or intussusception, which often indicates intestinal lymphoma. If children exhibit lymph node enlargement or deep lymph node enlargement is discovered through imaging studies, it is necessary to perform a puncture or biopsy and conduct a pathological examination to further confirm whether it is lymphoma.

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Written by Liu Liang

Oncology

1min 8sec

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Symptoms of Lymphoma

The symptoms of lymphoma mostly present as painless enlarged superficial lymph nodes, which are common clinical manifestations. Additionally, there may be enlargement of the liver and spleen, with multiple organs throughout the body possibly affected. In advanced stages, patients may experience invasion of the bone marrow. There are also special types of extranodal lymphomas which exhibit specific symptoms. For instance, lymphomas originating in the stomach may present with upper abdominal masses, or symptoms like anemia, weight loss, black stools, and even upper abdominal pain, nausea, and vomiting related to the gastrointestinal tract. If the lymphoma originates in the nasal cavity, known as NK/T-cell lymphoma, symptoms may include tinnitus, nasal congestion, runny nose, and nosebleeds, among others. Some lymphoma patients may also experience fever, generalized weakness, weight loss, collectively referred to as B symptoms.