Rheumatoid arthritis diagnostic tests

Written by Yang Ya Meng

Rheumatology

Updated on September 08, 2024

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The diagnostic tests for rheumatoid arthritis include blood tests and X-ray examinations. Blood tests include a complete blood count, inflammatory markers, erythrocyte sedimentation rate, C-reactive protein, and screening for various antibodies such as rheumatoid factor, anti-O, anti-CCP antibodies, and anti-AKA antibodies. Additionally, if there is significant pain in the hand joints, an X-ray of the hand joints can be taken. The X-ray can show whether there is any destruction of bone, osteoporosis, or other manifestations of rheumatoid disease. Based on these tests, it is generally possible to diagnose the specific type of rheumatoid disease.

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Written by Yang Ya Meng

Rheumatology

50sec

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Can rheumatoid arthritis be cured?

Rheumatoid arthritis is difficult to completely cure without medication, as it is a chronic inflammatory disease of the immune system that requires lifelong medication. The main treatment plans include the following three categories: The first category is anti-inflammatory and analgesic, which includes non-steroidal analgesics and low-dose corticosteroids. The second category, which is also the most important treatment, involves the use of immunosuppressants. Commonly used immunosuppressants include methotrexate and leflunomide. If the patient does not respond well to anti-inflammatory analgesics and immunosuppressants, treatment with biological agents may also be considered. (Medications should be used under the guidance of a doctor.)

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Written by Yang Ya Meng

Rheumatology

59sec

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The difference between rheumatic arthritis and rheumatoid arthritis

Rheumatic arthritis is a reactive joint pain that occurs after a streptococcal infection. In addition to joint pain, common symptoms include mitral valve stenosis in some patients, skin erythema, and some patients may also exhibit symptoms such as chorea. Patients with rheumatoid arthritis often show symmetrical swelling and pain in the joints of both hands. Blood tests reveal significantly elevated levels of rheumatoid factor, anti-CCP antibodies, and AK antibodies. Inflammatory indicators such as erythrocyte sedimentation rate and C-reactive protein also tend to be significantly elevated. The main difference between rheumatic arthritis and rheumatoid arthritis is that rheumatic arthritis can involve cardiac and skin pathologies, while rheumatoid arthritis primarily manifests as joint-related pathologies.

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Written by Liu Li Ning

Rheumatology

47sec

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What should I do if rheumatoid arthritis deforms the knee joint?

Rheumatoid arthritis and knee joint deformity are serious conditions that may require joint replacement surgery. For less serious cases, non-steroidal anti-inflammatory drugs, such as etoricoxib or celecoxib, are generally used to treat and alleviate symptoms. The onset of rheumatoid arthritis is associated with streptococcal infections. Clinically, joint deformities are rare, so if joint deformity occurs, it is important to investigate the possibility of rheumatoid arthritis. Since rheumatoid arthritis is an immune-mediated erosive arthritis that can lead to bone destruction and joint deformity, rheumatoid factor and anti-CCP antibodies can be tested for diagnostic differentiation.

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Written by Yang Ya Meng

Rheumatology

54sec

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Rheumatoid Arthritis Diagnostic Criteria

The diagnostic criteria for rheumatoid arthritis include, first, the presence of swelling and pain in multiple joints, especially characterized and significant in the smaller joints. Second, serological tests show elevated levels of antibodies, commonly rheumatoid factor and anti-CCP antibodies. If both are elevated, it is most meaningful. Third, the duration of joint swelling and pain should be more than six weeks. Fourth, we must also check some inflammatory markers for joints, such as elevated erythrocyte sedimentation rate and C-reactive protein. If these markers are elevated, and the patient has swelling and pain in multiple joints, then we can consider a diagnosis of rheumatoid arthritis.

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Written by Yang Ya Meng

Rheumatology

57sec

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How is rheumatoid arthritis treated?

Rheumatoid arthritis, also commonly referred to as internal rheumatoid arthritis, primarily has three major categories of treatment. The first category is anti-inflammatory and pain relief. The medications for anti-inflammatory pain relief include two types: the first type is non-steroidal pain relievers; for patients with very severe pain, a low dose of corticosteroids can be considered. The second category, which is also the most important treatment, involves the use of immunosuppressants. These immunosuppressants include drugs such as methotrexate and leflunomide. If the patient does not respond well to anti-inflammatory pain relief and immunosuppressants, treatment with biologics can also be considered.