The difference between rheumatic arthritis and rheumatoid arthritis

Written by Yang Ya Meng
Rheumatology
Updated on September 07, 2024
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Rheumatic arthritis is a reactive joint pain that occurs after a streptococcal infection. In addition to joint pain, common symptoms include mitral valve stenosis in some patients, skin erythema, and some patients may also exhibit symptoms such as chorea. Patients with rheumatoid arthritis often show symmetrical swelling and pain in the joints of both hands. Blood tests reveal significantly elevated levels of rheumatoid factor, anti-CCP antibodies, and AK antibodies. Inflammatory indicators such as erythrocyte sedimentation rate and C-reactive protein also tend to be significantly elevated. The main difference between rheumatic arthritis and rheumatoid arthritis is that rheumatic arthritis can involve cardiac and skin pathologies, while rheumatoid arthritis primarily manifests as joint-related pathologies.

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Written by Yang Ya Meng
Rheumatology
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Rheumatoid arthritis diagnostic tests

The diagnostic tests for rheumatoid arthritis include blood tests and X-ray examinations. Blood tests include a complete blood count, inflammatory markers, erythrocyte sedimentation rate, C-reactive protein, and screening for various antibodies such as rheumatoid factor, anti-O, anti-CCP antibodies, and anti-AKA antibodies. Additionally, if there is significant pain in the hand joints, an X-ray of the hand joints can be taken. The X-ray can show whether there is any destruction of bone, osteoporosis, or other manifestations of rheumatoid disease. Based on these tests, it is generally possible to diagnose the specific type of rheumatoid disease.

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Written by Yang Ya Meng
Rheumatology
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Rheumatoid Arthritis Diagnostic Criteria

The diagnostic criteria for rheumatoid arthritis include, first, the presence of swelling and pain in multiple joints, especially characterized and significant in the smaller joints. Second, serological tests show elevated levels of antibodies, commonly rheumatoid factor and anti-CCP antibodies. If both are elevated, it is most meaningful. Third, the duration of joint swelling and pain should be more than six weeks. Fourth, we must also check some inflammatory markers for joints, such as elevated erythrocyte sedimentation rate and C-reactive protein. If these markers are elevated, and the patient has swelling and pain in multiple joints, then we can consider a diagnosis of rheumatoid arthritis.

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Written by Li Jing
Rheumatology
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What is the best medicine to take for rheumatoid arthritis?

Rheumatoid arthritis is a clinical manifestation of rheumatic fever, which is a delayed sequelae that occurs after infection with streptococci. The most common symptoms include fever, arthritis, rheumatic heart disease, subcutaneous nodules, or marginal erythema. It mainly occurs in adolescents and is most commonly triggered by cold weather and damp environments. In cases showing joint symptoms, the first choice of medication is nonsteroidal anti-inflammatory drugs (NSAIDs). Additionally, it is crucial to actively treat the primary disease, which means eliminating the causative factor by eradicating the streptococcal infection. Eradication of the streptococcal infection involves the use of long-acting penicillin, and it is necessary to complete the treatment course of two weeks. Moreover, appropriate rest during the acute phase and avoiding exertion is needed. (Please use medication under the guidance of a professional physician and do not self-medicate.)

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Written by Guan Yu Hua
Orthopedic Surgery
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Difference between arthritis and rheumatoid arthritis

Arthritis is typically osteoarthritis, a chronic inflammation characterized primarily by degenerative changes in joint cartilage, followed by bone proliferation, making it a chronic disease. Early pathological changes include alterations in joint cartilage, such as subchondral bone extrusion, followed by changes in the muscles surrounding the periosteum and joint capsule. Early radiographic examinations can provide a definitive diagnosis. Its symptoms primarily manifest as pain. For rheumatoid arthritis, it generally presents as morning stiffness and joint swelling and pain more severe than in the surrounding area, which can essentially confirm a diagnosis. It usually affects large joints such as the knee, shoulder, or wrist joints, typically presenting as migratory pain. A definitive diagnosis can usually be made by testing for rheumatoid factor, with an anti-O level exceeding 500 units. Additionally, there may be a slight increase in white blood cells, accelerated erythrocyte sedimentation rate, and elevated C-reactive protein. Examination of the synovial fluid shows increased white blood cells and neutrophils. In such cases, using anti-rheumatic drugs might suffice, but it’s also crucial to ensure rest and local heat application. These two types of arthritis fundamentally differ.

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Written by Yang Ya Meng
Rheumatology
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How to cure rheumatoid arthritis?

The treatment methods for rheumatoid arthritis mainly consist of three major categories. The first category is the use of anti-inflammatory and analgesic drugs, commonly including non-steroidal analgesics such as sustained-release diclofenac sodium tablets, and small doses of corticosteroids can also be used. For rheumatoid arthritis, the most important treatment is the choice of immunosuppressants. Commonly used immunosuppressants include methotrexate and leflunomide. After using these medications, it is necessary to regularly monitor blood routine tests and liver and kidney functions to check for possible side effects of the drugs. If the effects of the above oral medications are not satisfactory, the application of biologics can also be considered. (Specific medications should be used under the guidance of a doctor, do not self-medicate.)