Rheumatoid arthritis, also commonly referred to as internal rheumatoid arthritis, primarily has three major categories of treatment. The first category is anti-inflammatory and pain relief. The medications for anti-inflammatory pain relief include two types: the first type is non-steroidal pain relievers; for patients with very severe pain, a low dose of corticosteroids can be considered. The second category, which is also the most important treatment, involves the use of immunosuppressants. These immunosuppressants include drugs such as methotrexate and leflunomide. If the patient does not respond well to anti-inflammatory pain relief and immunosuppressants, treatment with biologics can also be considered.