Hand, foot, and mouth disease is a viral infection caused by an enterovirus infection, mainly manifesting as exanthematous disease with maculopapular and vesicular rashes on the hands, feet, mouth, and buttocks. It is a contagious disease with relatively strong transmissibility, mainly spread through the respiratory tract, digestive tract, and close contact. Therefore, once a child is diagnosed with hand, foot, and mouth disease, isolation measures must be taken, and the child should not attend kindergarten or school to avoid infecting other healthy children. Additionally, to prevent the occurrence of hand, foot, and mouth disease, it is crucial to ensure proper ventilation by opening windows during the epidemic period to avoid causing an outbreak of the disease.