Is uremia hereditary?

Written by Zhou Qi
Nephrology
Updated on September 29, 2024
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Uremia is not actually an independent disease, so it's difficult to say that uremia is hereditary. Uremia refers to a condition where the kidneys are 90% damaged. However, there are many reasons that can cause more than 90% of kidney tissue damage; among these, some are genetic diseases, but most are not hereditary. Common causes of hereditary uremia include diabetes, as well as primary chronic glomerulonephritis, hypertension, urinary system stones, and even prostate tumors, allergic purpura, etc., which can all cause kidney damage. These factors are generally not genetic diseases. However, there are very few causes of uremia that are genetic diseases, mainly including autosomal dominant polycystic kidney disease.

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Can uremia be cured?

First, it is necessary to clarify the cause and the severity, so it is important to visit the nephrology department for comprehensive tests. Once the cause is determined, the next steps can be planned based on the results, and dialysis may be necessary if required. If there is no improvement, treatments such as kidney transplantation can be considered. It is also crucial to rest, avoid fatigue, reduce activities, especially strenuous activities, maintain a positive mood, adjust your mentality, and have regular follow-ups. Therefore, this issue needs to be actively addressed, as it can be very troublesome to manage and the prognosis may be very poor if not taken seriously.

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Does uremia cause blood in urine?

Patients with uremia may experience hematuria, but not all patients will do so. Uremia refers to a condition where over 90% of the patient's kidney tissue has been damaged. Due to the destruction of kidney tissue, when blood passes through the kidneys, it is indeed possible that red blood cells will leak from the glomeruli into the urine. Therefore, patients with uremia may exhibit signs of hematuria, especially those caused by primary chronic glomerulonephritis. If the uremia is caused by tumors or kidney stones leading to urinary obstruction, this situation can cause bleeding in the ureters or bladder, also resulting in hematuria. However, most patients with uremia have a very low chance of experiencing hematuria because the vast majority of their kidney tissue has been destroyed, even up to 100%, leaving no urine production, and thus no blood in the urine. If an anuric patient exhibits hematuria, the possibility of stones, tumors, or urinary tract infections should be considered.

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Is uremia cancer?

Uremia is not cancer. Chronic kidney failure refers to the presence of various kidney diseases that lead to a progressive and irreversible decline in kidney function, culminating in a series of symptoms and metabolic disorders that form a clinical syndrome, commonly known as chronic kidney failure. The end stage of chronic kidney failure is what is often referred to as uremia. Uremia is not a separate disease, but a clinical syndrome common to various late-stage kidney diseases. It is a symptom consisting of a series of clinical manifestations that occur when chronic kidney failure enters its terminal stage. Typically, this includes disturbances in water and electrolyte acid-base metabolism, with metabolic acidosis and water-electrolyte imbalance being the most common.

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Written by Zhou Qi
Nephrology
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Does uremia hurt?

The so-called uremia refers to patients whose kidney function has been lost by more than 90%, and the vast majority of kidney tissue has been destroyed. Although the condition of these patients is very serious, they do not experience pain symptoms. In patients with uremia, the kidney tissue has hardened, and in most of the causes leading to uremia, pain is not induced. Even though the kidneys have severe problems, there are no nerves in the kidneys to sense pain, as there are no sensory nerves, so the kidneys do not feel pain. Causes that can lead to uremia include diabetes, hypertension, chronic nephritis, urinary system stones, tumors, and more. Painful conditions are mainly caused by urinary system stones, while other causes generally do not entail pain.

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Written by Zhou Qi
Nephrology
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Is uremia hereditary?

Uremia is not actually an independent disease, so it's difficult to say that uremia is hereditary. Uremia refers to a condition where the kidneys are 90% damaged. However, there are many reasons that can cause more than 90% of kidney tissue damage; among these, some are genetic diseases, but most are not hereditary. Common causes of hereditary uremia include diabetes, as well as primary chronic glomerulonephritis, hypertension, urinary system stones, and even prostate tumors, allergic purpura, etc., which can all cause kidney damage. These factors are generally not genetic diseases. However, there are very few causes of uremia that are genetic diseases, mainly including autosomal dominant polycystic kidney disease.