Does uremia cause blood in urine?

Written by Zhou Qi
Nephrology
Updated on April 25, 2025
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Patients with uremia may experience hematuria, but not all patients will do so. Uremia refers to a condition where over 90% of the patient's kidney tissue has been damaged. Due to the destruction of kidney tissue, when blood passes through the kidneys, it is indeed possible that red blood cells will leak from the glomeruli into the urine. Therefore, patients with uremia may exhibit signs of hematuria, especially those caused by primary chronic glomerulonephritis. If the uremia is caused by tumors or kidney stones leading to urinary obstruction, this situation can cause bleeding in the ureters or bladder, also resulting in hematuria. However, most patients with uremia have a very low chance of experiencing hematuria because the vast majority of their kidney tissue has been destroyed, even up to 100%, leaving no urine production, and thus no blood in the urine. If an anuric patient exhibits hematuria, the possibility of stones, tumors, or urinary tract infections should be considered.

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Written by Huang Feng Fei
Urology
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Why would someone get uremia?

Uremia, also known as end-stage renal failure, has many causes. Common surgical conditions include urological obstructions such as urethral blockage, kidney tumors, malformations, kidney cancer, and others, as well as numerous kidney cysts, all of which can lead to renal failure. Common internal medicine causes include chronic glomerulonephritis, long-standing hypertension, hypertensive nephropathy, diabetes, diabetic nephropathy, etc., which can also lead to renal failure. In summary, end-stage renal failure is referred to as uremia.

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Written by Zhou Qi
Nephrology
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Is high creatinine uremia?

High creatinine levels do not necessarily indicate uremia. High creatinine often implies that the patient is experiencing renal failure, which can be classified into acute renal failure and chronic renal failure based on factors such as the patient's medical history and course of the disease. Uremia is the final state of chronic renal failure. Thus, even if high creatinine levels suggest the possibility of chronic renal failure, it does not necessarily mean that the patient has reached the final stage. Uremia, also known as end-stage renal disease, generally requires a patient's blood creatinine to exceed 707 µmol/L. Additionally, patients often simultaneously present with clinical manifestations such as renal anemia, disorders of calcium and phosphorus metabolism, and reduction in kidney size.

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Written by Li Fang Xiao
Internal Medicine
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Early symptoms of uremia in women

Uremia is a terminal stage of many kidney diseases. In the early stages of uremia, symptoms such as nausea and vomiting related to the gastrointestinal tract often appear. Other symptoms can include itchy skin and a dull complexion. For women, complications such as menstrual disorders and irregular menstruation may occur. In such cases, it is necessary to go to the hospital to check kidney function and determine the specific levels of creatinine and urea. If creatinine exceeds 700, it generally reaches the level of uremia, requiring renal replacement therapy such as hemodialysis or peritoneal dialysis. For uremia, it is most important to control the intake of salt and water in the diet, avoid high-salt food, and also avoid drinking too much water to prevent fluid retention in the body, thereby endangering life, as this can lead to heart failure or severe edema.

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Written by Tang Da Wei
General Surgery
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Can holding urine lead to uremia?

Holding urine will not cause uremia. Holding urine may lead to bladder fullness, and after a long time, it might cause dilation of the ureters, but it will not lead to uremia. Uremia is caused by renal insufficiency or end-stage renal failure, characterized by significantly increased creatinine and urea nitrogen in the patient's body, with reduced urine output or even anuria. Once uremia is diagnosed, it generally requires hospitalization for dialysis treatment, which involves removing toxins from the body through dialysis. Additionally, it is advised to consume nutritionally rich foods in daily life.

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Written by Zou De Bo
Urology
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Can holding urine cause uremia?

Generally speaking, holding urine does not lead to uremia, but if the bladder is overfilled, it can result in an inability to urinate. This can lead to acute renal dysfunction. After catheterization, the indicators of renal function can quickly return to normal. Therefore, we should try to avoid holding urine as much as possible and go to the bathroom promptly when we need to. This is something we should pay attention to in our daily lives.