How long can one live after prostate cancer has spread to the bones?

Written by Zhou Zi Hua

Oncology

Updated on September 17, 2024

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Bone metastasis is the most common site of metastasis for prostate cancer. If a patient with prostate cancer develops bone metastasis, it means that the cancer is no longer in its early stages and has progressed to a more advanced stage. However, unlike other cancers with a higher degree of malignancy, if the tumor is highly sensitive to hormone therapy, with standardized treatment, the patient's survival time can be significantly extended.

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Is chemotherapy for prostate cancer painful?

For patients with advanced prostate cancer, endocrine therapy is primarily used. Chemotherapy is generally chosen when endocrine therapy is resistant and ineffective. The side effects of chemotherapy are similar to those of other chemotherapy treatments. The first is the gastrointestinal side effects, such as nausea, vomiting, decreased appetite, or bloating and abdominal pain. The second is bone marrow suppression, which leads to a decrease in white blood cells and platelets. The side effects of chemotherapy vary with each patient's constitution and other factors. In most cases, with the support of medications for stomach protection, anti-nausea, and increasing white blood cells, the majority of patients can generally tolerate the treatment.

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Prostate cancer IV is stage 4.

Prostate cancer stage IV refers to stage four prostate cancer, which is a common type of male reproductive organ tumor, particularly prevalent among elderly men. Stage four prostate cancer means that the tumor is not confined to the prostate and has already shown corresponding distant metastasis. The most common sites of metastasis for prostate cancer are the bones, followed by the lungs, liver, and others. When metastasis of prostate cancer occurs, it is considered to be at a late stage, and the primary treatments include endocrine therapy, chemotherapy, etc., with a poor prognosis.

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How is prostate cancer detected?

Digital rectal examination combined with PSA testing is currently recognized as the best screening method for the early detection of prostate cancer. Currently, systematic prostate needle biopsy is the most reliable method for diagnosing prostate cancer. In addition, prostate cancer MRI plays an important role in clinical staging. There is also a whole-body nuclear bone marrow scan that can detect the most common metastatic sites of prostate cancer, including bone metastases.

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Commonly used drugs for endocrine treatment of prostate cancer

The purpose of endocrine therapy for prostate cancer is to reduce the concentration of androgens in the body, inhibit the synthesis of androgens originating from the adrenal glands, inhibit the conversion of testosterone to dihydrotestosterone, or block the binding of androgens to their receptors, thereby inhibiting or controlling the growth of prostate cancer cells. The medications include a luteinizing hormone-releasing hormone analogue, with representative drugs being leuprorelin, goserelin, and triptorelin. There is also an androgen-blocking drug, including steroidal drugs with representative drugs like cyproterone acetate, and non-steroidal drugs with representative drugs like bicalutamide and flutamide. Additionally, there are estrogens, with the most common being diethylstilbestrol.

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Can prostate cancer be cured?

Prostate cancer, whether it can be cured or not, depends on the specific analysis of the patient with prostate cancer. If it is an early-stage patient, meaning there is no metastasis to distant organs, and it is assessed that radical surgery or radical radiotherapy can be performed, then these early-stage prostate cancer patients still have the hope of being cured through these treatment methods. However, for patients with advanced prostate cancer, such as those who are diagnosed with multiple bone metastases at the onset—a very common clinical occurrence, prostate cancer combined with bone metastasis is very common—these advanced-stage prostate cancer patients cannot be cured through treatment. The purpose of treatment is to alleviate the patient's pain and extend the patient's survival, but these advanced-stage patients cannot be cured.