The difference between esophageal cancer and laryngeal cancer

Written by Liu Liang
Oncology
Updated on September 13, 2024
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Esophageal cancer and laryngeal cancer are both malignant tumors. Esophageal cancer refers to the malignant tumor occurring in the esophagus, while laryngeal cancer refers to the malignant tumor occurring in the larynx. Therefore, their tumor locations are different. The pathology of both is generally squamous cell carcinoma. The main symptom of esophageal cancer is obstructed eating; patients will feel difficulty swallowing, obstruction, and worsening of these symptoms as they eat. The primary symptom of laryngeal cancer is typically a hoarse voice, which distinguishes the symptoms of the two cancers.

Other Voices

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Written by Xu Qing Tian
Otolaryngology
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Recurrence rate after total laryngectomy for throat cancer

Laryngeal cancer is a common disease in otolaryngology and a relatively prevalent malignant tumor. Patients who undergo total laryngectomy often have advanced laryngeal tumors, which block the esophagus or pharynx and have tumor tissues too large for partial removal. The likelihood of recurrence after tumor resection varies from patient to patient, depending on the radiotherapy and chemotherapy administered post-operatively, as well as individual physical constitutions, which can alter recurrence rates. Generally, we recommend that patients undergo a laryngoscopic check-up every three to six months and a CT scan of the larynx post-surgery, to enable timely detection and treatment, aiming for early control and intervention in case of potential recurrence.

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Written by Li Rui
Otolaryngology
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What age does throat cancer generally occur?

Throat cancer is a relatively common type of malignant tumor in the head and neck region. It more commonly affects middle-aged or elderly men, with most patients being over 40 years old. Specific clinical symptoms vary among individuals, but common symptoms include sore throat and hoarseness. Some patients may experience difficulty breathing. In terms of treatment, surgery and radiation therapy are commonly used, and some patients may require a combination of comprehensive treatment plans. Regular follow-ups are necessary during the treatment process to monitor the effectiveness of the treatment.

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Written by Li Mao Cai
Otolaryngology
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Is a hoarse voice an indication of throat cancer?

Hoarseness does not necessarily indicate laryngeal cancer because there are many diseases that can cause hoarseness. Common ones include vocal cord nodules, vocal cord polyps, acute laryngitis, chronic laryngitis, vocal cord grooves, and laryngeal cancer. The primary approach should be to visit an ENT (Ear, Nose, and Throat) department in a hospital, undergo an electronic fibrolaryngoscopy, and then determine the specific lesion based on the examination results. It is incorrect to diagnose laryngeal cancer based solely on hoarseness. For instance, some types of laryngeal cancer, such as supraglottic or subglottic, may cause hoarseness symptoms to appear late or even not at all. Therefore, while hoarseness does not necessarily mean laryngeal cancer, laryngeal cancer can potentially cause hoarseness. It is crucial to seek timely medical attention and undergo electronic fibrolaryngoscopy for a basic definitive diagnosis when hoarseness occurs. Apart from diseases of the throat, conditions affecting the thyroid, mediastinum, and esophagus can also cause hoarseness when they progress to a certain stage. Thus, hoarseness is a symptom that can be caused by many diseases, but it is not necessarily indicative of laryngeal cancer. Supraglottic laryngeal cancer, however, can manifest hoarseness as an early symptom. Therefore, it is critical to seek medical attention promptly once this symptom occurs.

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Written by Li Mao Cai
Otolaryngology
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Early symptoms of throat cancer

The early symptoms of laryngeal cancer vary depending on the type, as laryngeal cancer is categorized into three types. The most common type, accounting for over 80%, is glottic cancer. The early symptom for this type is primarily hoarseness, making it the type of laryngeal cancer where symptoms appear earliest. The other two types are supraglottic and subglottic cancer. These types are less likely to show early symptoms, or the symptoms may not be typical and easily noticeable or taken seriously. The main symptom is a foreign body sensation in the throat, which is often mistaken for pharyngitis or laryngitis and not given due attention. Therefore, when experiencing persistent hoarseness or a noticeable foreign body sensation in the throat, and if throat discomfort persists, it is advised to visit the Ear, Nose, and Throat (ENT) department of a hospital promptly for an examination with an electronic laryngoscope. This can help in the early detection, exclusion, and diagnosis of the condition.

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Written by Zhang Jun
Otolaryngology
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Where is throat cancer likely to metastasize?

The metastasis of laryngeal cancer primarily involves local spread, mainly to the lymph nodes in zones 2, 3, and 4 of the neck. When the cancer becomes more severe, it can break through the lymphatic vessels and spread to the liver, kidneys, spleen, brain, lungs, and other related areas. Laryngeal cancer is a malignant tumor of the pharyngeal region, typically caused by long-term smoking, drinking, immunodeficiency, and cellular mutations. It commonly occurs in the vocal cords, esophagus, laryngeal ventricle, piriform sinus, base of the tongue, and epiglottis. It causes patients to feel a foreign body sensation in the throat, persistent hoarseness that progressively worsens, irritative cough, difficulty swallowing, and difficulty breathing. An examination with an electronic laryngoscope can help diagnose the condition. If an abnormal mass is found, a local biopsy is necessary. If laryngeal cancer is confirmed, related surgical treatment as well as radiotherapy or chemotherapy may be required.