Recurrence rate after total laryngectomy for throat cancer

Written by Xu Qing Tian
Otolaryngology
Updated on February 01, 2025
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Laryngeal cancer is a common disease in otolaryngology and a relatively prevalent malignant tumor. Patients who undergo total laryngectomy often have advanced laryngeal tumors, which block the esophagus or pharynx and have tumor tissues too large for partial removal. The likelihood of recurrence after tumor resection varies from patient to patient, depending on the radiotherapy and chemotherapy administered post-operatively, as well as individual physical constitutions, which can alter recurrence rates. Generally, we recommend that patients undergo a laryngoscopic check-up every three to six months and a CT scan of the larynx post-surgery, to enable timely detection and treatment, aiming for early control and intervention in case of potential recurrence.

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Oncology
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Symptoms and Early Signs of Throat Cancer

Symptoms and signs of laryngeal cancer in patients mainly vary according to the different locations of the tumor in the larynx. Most patients with early-stage laryngeal cancer experience a foreign body sensation in the throat, which can be persistent. Patients may even feel a choking sensation when swallowing. Additionally, some patients with early-stage laryngeal cancer may experience unexplained hoarseness or coughing and choking when drinking water, and these symptoms generally do not respond well to oral medication. Some patients exhibit frequent coughing, and ordinary symptomatic cough treatments are ineffective. These are mostly early symptoms and signs. As the laryngeal cancer progresses, patients will experience a noticeable obstruction in the throat, along with symptoms like difficulty breathing.

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Written by Li Rui
Otolaryngology
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Can throat cancer be detected by a CT scan?

Most laryngeal cancers can be detected through CT scans because, during the scan, it is possible to see whether there are neoplasms in the area of the pharynx and larynx, especially around the laryngeal cavity, ventricle, and vocal cords. Generally, if there are any growths, they will be visible on a CT scan. However, some early-stage laryngeal cancers, where the mucosa has just started to show changes, might be missed by CT scans. In such cases, it is generally recommended to also perform a laryngoscopic examination. If possible, conducting an NBI (Narrow Band Imaging) laryngoscopy could reveal early mucosal changes. If early-stage laryngeal cancer is confirmed by pathology, surgical or radiation treatment can be very effective and generally has a low chance of recurrence.

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Written by Xu Qing Tian
Otolaryngology
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How long does it take for throat cancer to develop?

Throat cancer is a common malignant tumor in otolaryngology, which usually forms over the course of a year or half a year. However, patients typically have long-term chronic stimuli and medical history before the tumor changes occur, such as a long history of smoking or drinking, as well as exposure to physical and chemical factors. Early symptoms of throat cancer often include hoarseness, while in the mid to late stages, patients may experience difficulty swallowing and breathing difficulties. We can make a definite diagnosis through local pathological biopsy, electronic laryngoscopy, and CT scans of the throat area. Early detection of throat cancer should lead to timely surgical treatment, followed by radiotherapy and chemotherapy. For late-stage patients who are not suitable for surgery, chemotherapy or radiotherapy should be administered promptly to extend the patient's lifespan.

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Written by Li Rui
Otolaryngology
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How to distinguish between throat cancer and pharyngitis.

Laryngeal cancer and pharyngitis are fundamentally different. First, there is the specific nature of the lesions: laryngeal cancer is a type of malignant tumor in the pharyngeal and laryngeal areas, posing significant health risks; whereas pharyngitis is a common clinical symptom in the pharyngeal and laryngeal areas, mainly caused by inflammatory reactions, and may involve sensations of a foreign body in the throat, pain, and burning, but overall, it poses less risk to health. Additionally, the specific sites of disease onset differ. The lesions in laryngeal cancer primarily occur in the vocal cord area, with some in the supraglottic or subglottic areas, where new growths might be found, which can be identified through pathological biopsy. In contrast, pharyngitis primarily involves chronic congestion and inflammatory reactions of the mucous membranes in the pharyngeal area, with no direct new growth, which can be directly diagnosed and differentiated through pathological biopsy.

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What causes throat cancer?

Laryngeal cancer is a common malignant tumor in daily life. Its occurrence is due to factors related to long-term smoking, drinking, and stimulation from physical and chemical factors in the air or work environment. For patients with laryngeal cancer, it is usually necessary to make a definitive diagnosis through examinations such as electronic nasopharyngoscopy, electronic laryngoscopy, and CT of the larynx. Particularly when the patient presents symptoms such as hoarseness, cough with blood, and breathing difficulty, it should draw the patient's attention to seek timely medical examination at a hospital, aiming for early detection and early treatment.