Bile reflux gastritis is primarily due to significant partial gastrectomy or gastrojejunostomy, as well as pyloric dysfunction or chronic biliary diseases, including bacterial infections, especially Helicobacter pylori infection. Moreover, inflammation is caused by damage to the gastric mucosa from bile and gastric acid, which affects gastrointestinal motility. This leads to disordered coordinated movements of the gastrointestinal tract and disturbances in gastrointestinal motility, such as abnormal hormone levels and gastrointestinal neuropeptides. All these factors can lead to gastrointestinal dysfunction, which can result in bile reflux.