Cervical biopsy is used to examine cervical lesions. Patients with bleeding or irregular vaginal bleeding should undergo cervical cancer screening, generally starting with a TCT and HPV test, or a cervical biopsy if cervical lesions are suspected. If there are abnormalities in the TCT or HPV test, a cervical biopsy may be needed. Cervical biopsy is a test for cervical cancer screening, while syphilis testing must be done through serological testing. A cervical biopsy cannot detect the presence of syphilis, as these two tests are unrelated; therefore, a cervical biopsy cannot determine the presence of syphilis.