What is the typical titer for third-stage syphilis?
Updated on May 21, 2025
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The titers of tertiary syphilis are generally lower than those of primary and secondary syphilis. Syphilis is divided into three stages. During the primary and secondary stages, the reactivity of the Treponema pallidum is higher, thus the titers are also higher. However, the titers for tertiary syphilis often appear lower or even negative. The level of syphilis titers is not significantly related to the duration of the illness. Interestingly, tertiary syphilis generally occurs when the disease has already progressed for more than two years, which results in lower titers.
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