Third-stage syphilis has no symptoms.

Written by Zhu Zhu

Dermatology

Updated on January 01, 2025

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Once tertiary syphilis has developed, it is highly unlikely for there to be no symptoms. Tertiary syphilis is a late stage of the disease, generally involving the skin, mucous membranes, cardiovascular system, and even the motor and nervous systems. If there are no symptoms present, it is generally not possible to be in the tertiary stage of syphilis. Therefore, if tertiary syphilis occurs, it will not be without symptoms.

Other Voices

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Written by Li Cui

Dentistry

58sec

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Is frequent oral ulceration related to syphilis?

Mouth ulcers are not related to syphilis. Mouth ulcers involve the breakdown of mucous membrane tissues inside the mouth, which can appear as one or several ulcerative lesions, sometimes showing a milky-white appearance, along with possible milky-white peeling. Therefore, they are not connected to syphilis, and patients are advised not to worry excessively. Syphilis is a sexually transmitted disease that can cause ulceration throughout the body. Mouth ulcers generally occur due to internal heat or a weakened immune system in the affected individual. If a patient frequently experiences mouth ulcers, it is advisable to visit a hospital to rule out other systemic diseases. Additionally, it is important to consider whether these could be related to a deficiency in certain vitamins, so patients are advised not to be overly anxious.

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Written by Zhu Zhu

Dermatology

47sec

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How long does it take to cure third-stage syphilis?

Third-stage syphilis is the most severe stage of the disease. It generally damages the nervous system and cardiovascular system of the human body, thus having a significant impact. There is no definite timeline for the cure of third-stage syphilis. The treatment of third-stage syphilis primarily involves controlling the condition with medication; there is still no specific method that can completely cure it thoroughly. Therefore, it is necessary to take medication for a long period. Currently, for treating third-stage syphilis, procaine penicillin is generally chosen for patients. In fact, procaine penicillin mainly helps effectively control the syphilis spirochete.

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Written by Luo Hong

Dermatology Department

52sec

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Syphilis IgM negative represents what?

Syphilis IgM negative, which is primarily screened using the ELISA method. Generally, a negative IgM can temporarily rule out syphilis. If still uncertain, further confirmatory syphilis tests can be conducted, such as TPPA (Treponema Pallidum Particle Agglutination) or TPHA (Treponema Pallidum Hemagglutination). Usually, syphilis can be temporarily dismissed if IgM is negative. However, if symptoms of a primary chancre are present, such as genital ulcers, an early Syphilis IgM might be negative. In such cases where symptoms are clear but IgM is negative, it is typically advised to retest after one month. If the result turns positive, a confirmatory test should be performed to diagnose and treat syphilis.

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Written by Li Cui

Dentistry

58sec

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Is severe oral ulceration related to syphilis?

Oral ulcers are a type of erosion of the mucous membrane in the mouth and are commonly seen in clinical settings; they are a common disease. Syphilis, on the other hand, is a viral infection unrelated to oral ulcers, so it is recommended that patients be aware to differentiate them. Furthermore, it is crucial for patients to pay attention to their lifestyle habits and personal hygiene. When oral ulcers occur, it is appropriate to use some medications for oral ulcers for application, which can effectively treat the ulcerated surface of the mouth. Moreover, if a patient experiences severe, recurrent oral ulcers, it is advised to seek medical diagnosis at a hospital to exclude the possibility of other systemic diseases causing the ulcers. Additionally, patients should maintain good oral hygiene daily to develop healthy oral habits.

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Written by Zhu Zhu

Dermatology

43sec

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When is the third stage of syphilis?

Tertiary syphilis is a relatively late stage of syphilis, often occurring two to three years after the initial detection of the disease. For patients with a longer course of the disease, it generally appears five to ten years later. Once tertiary syphilis is diagnosed, it is often accompanied by damage to various organ functions, such as the cardiovascular system, bones, skin, and nervous system. Therefore, it is crucial to detect and treat syphilis early and to follow standard treatment protocols with a doctor. Otherwise, once it progresses to tertiary syphilis, it becomes very difficult to cure.