Tertiary syphilis is a relatively late stage of syphilis, often occurring two to three years after the initial detection of the disease. For patients with a longer course of the disease, it generally appears five to ten years later. Once tertiary syphilis is diagnosed, it is often accompanied by damage to various organ functions, such as the cardiovascular system, bones, skin, and nervous system. Therefore, it is crucial to detect and treat syphilis early and to follow standard treatment protocols with a doctor. Otherwise, once it progresses to tertiary syphilis, it becomes very difficult to cure.