Oral ulcers are a type of erosion of the mucous membrane in the mouth and are commonly seen in clinical settings; they are a common disease. Syphilis, on the other hand, is a viral infection unrelated to oral ulcers, so it is recommended that patients be aware to differentiate them. Furthermore, it is crucial for patients to pay attention to their lifestyle habits and personal hygiene. When oral ulcers occur, it is appropriate to use some medications for oral ulcers for application, which can effectively treat the ulcerated surface of the mouth. Moreover, if a patient experiences severe, recurrent oral ulcers, it is advised to seek medical diagnosis at a hospital to exclude the possibility of other systemic diseases causing the ulcers. Additionally, patients should maintain good oral hygiene daily to develop healthy oral habits.