Colds in children can potentially lead to encephalitis, and are generally referred to as upper respiratory tract infections in children. The pathogens can be bacteria, viruses, etc., typically manifesting as fever, runny nose, sneezing, coughing, sore throat, and more.

Sometimes, gastroenteric colds can also manifest as nausea, vomiting, abdominal pain, diarrhea, etc. Because children have relatively lower immunity, if the infecting pathogen is highly toxic and aggressive, it can potentially cross the blood-brain barrier and enter the brain tissue, causing encephalitis. When encephalitis occurs in children, symptoms such as fever, seizures, and coma can appear, and neurological signs may be observed upon examination.