The likelihood of a wound being infected with tetanus

Written by Gao Sen
General Surgery
Updated on November 01, 2024
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Tetanus is a specific infection often associated with trauma, with a high contamination rate of tetanus bacillus in traumatic wounds. On the battlefield, the contamination rate can reach 25% to 80%, although the incidence of tetanus in contaminated wounds is only about 10% to 20%. This suggests that other factors are necessary for the disease to occur, with the main factor being an anaerobic environment. If the wound is deep, with a small external opening, and contains necrotic tissue, blood clots, or is too tightly packed, this can lead to local ischemia. Additionally, if there is a co-infection with aerobic bacteria consuming residual oxygen in the wound, it creates an anaerobic environment conducive to the growth of the bacteria, thus increasing the likelihood of tetanus infection in the wound.

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Written by Xu Jun Hui
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How to administer a tetanus shot if it is negative?

A negative tetanus needle test indicates that the patient is not allergic to the tetanus antitoxin and can continue with intramuscular injections, typically administered in the upper arm or buttock muscles, in doses ranging from 1000 to 3000 units each time. If the infection is severe or the tetanus injection is not timely, the dosage may be appropriately increased, generally by one to two times. The purpose of administering tetanus antitoxin treatment is to prevent infection by Clostridium tetani, an anaerobic bacterium. For patients with deep wounds or heavily contaminated wounds, such as those contaminated with soil or rust, Clostridium tetani can easily colonize. Therefore, for such patients, it is essential to perform tetanus antitoxin treatment while cleaning and dressing the wound.

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What should I do if the tetanus test is positive?

A positive tetanus result generally refers to a positive result in the tetanus antitoxin skin test. Tetanus antitoxin is primarily used to prevent tetanus infections. Some patients may experience allergic reactions to tetanus, manifesting as localized swelling, mild fever, and general discomfort during the skin test. In such cases, a desensitization injection method can be chosen, which involves administering the tetanus shot in several doses at intervals. Alternatively, tetanus immunoglobulin can be used, which is more expensive on the market but has the advantage of not requiring a skin test. It can be administered directly, safely, and effectively.

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Written by Li Xiao Lin
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What are the situations for tetanus shots?

Objects carrying tetanus bacillus, or tissues damaged by animals, require tetanus vaccination to prevent tetanus, such as rusty nails, animal claws, animal bites, venomous snake bites, and wounds contaminated by dirt can easily lead to infection by tetanus bacillus. Tetanus is a possible condition, so after an injury, it is necessary to immediately rinse the wound with soap and water or running water to wash away the toxins, which helps reduce the chance of infection. Then thoroughly disinfect the wound with iodophor, which can also reduce infection, and go to the hospital to receive tetanus antitoxin or tetanus immunoglobulin within 24 hours to prevent the onset of tetanus. The incubation period for tetanus is generally three to seven days, but it can be longer, so it is advised to go to the hospital for an injection as soon as possible after injury, to prevent the onset of the disease and avoid serious events.

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How long do you have to get a tetanus shot?

It is generally recommended to receive an injection as soon as possible after a trauma, ideally within 24 hours, because tetanus has a certain incubation period, with the shortest being able to cause disease within 24 hours. There is still value in receiving the injection after 24 hours; it can alleviate symptoms and play a preventive treatment role. For tetanus, it is usual to administer a tetanus shot, and most people can choose between tetanus antitoxin or tetanus immunoglobulin. The duration of these two drugs is not the same; tetanus antitoxin lasts about three days, while tetanus immunoglobulin can last up to three weeks. However, this is not an absolute conclusion. Beyond this time, if there are high-risk factors for reinfection, a repeat injection is needed. If a patient has previously been protected by an active immunization regimen, in most cases, no special preventive treatment is needed within three years of the last vaccination.

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How long does it take for tetanus to develop?

Tetanus is a specific type of infection caused by the toxin produced by the growth and reproduction of Clostridium tetani, which enters the body through damaged skin and mucous membranes and thrives in an anaerobic environment. Clinically, it is mainly characterized by lockjaw, muscle rigidity, and muscle spasms. After being infected with tetanus, people generally show symptoms within seven to eight days; in quick cases, symptoms can appear within twenty-four hours, while in longer scenarios, the onset can take several months or even years.