How to administer a tetanus shot if it is negative?

Written by Xu Jun Hui
General Surgery
Updated on November 11, 2024
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A negative tetanus needle test indicates that the patient is not allergic to the tetanus antitoxin and can continue with intramuscular injections, typically administered in the upper arm or buttock muscles, in doses ranging from 1000 to 3000 units each time. If the infection is severe or the tetanus injection is not timely, the dosage may be appropriately increased, generally by one to two times. The purpose of administering tetanus antitoxin treatment is to prevent infection by Clostridium tetani, an anaerobic bacterium. For patients with deep wounds or heavily contaminated wounds, such as those contaminated with soil or rust, Clostridium tetani can easily colonize. Therefore, for such patients, it is essential to perform tetanus antitoxin treatment while cleaning and dressing the wound.

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Written by Zhang Peng
General Surgery
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How long do you have to get a tetanus shot?

It is generally recommended to receive an injection as soon as possible after a trauma, ideally within 24 hours, because tetanus has a certain incubation period, with the shortest being able to cause disease within 24 hours. There is still value in receiving the injection after 24 hours; it can alleviate symptoms and play a preventive treatment role. For tetanus, it is usual to administer a tetanus shot, and most people can choose between tetanus antitoxin or tetanus immunoglobulin. The duration of these two drugs is not the same; tetanus antitoxin lasts about three days, while tetanus immunoglobulin can last up to three weeks. However, this is not an absolute conclusion. Beyond this time, if there are high-risk factors for reinfection, a repeat injection is needed. If a patient has previously been protected by an active immunization regimen, in most cases, no special preventive treatment is needed within three years of the last vaccination.

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Written by Li Jin Quan
General Surgery
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Can tetanus be fatal?

Tetanus can be fatal if not treated promptly. When infected with tetanus, early symptoms primarily include dizziness, headache, fatigue, decreased appetite, weak chewing, and sore jaw muscles, some may also exhibit increased reflexes or muscle rigidity. As the condition worsens, some patients show typical tetanus symptoms such as lockjaw, difficulty opening the mouth, risus sardonicus, opisthotonos, and stiff neck. As the condition further deteriorates, it can lead to difficulty breathing, or even respiratory arrest, and cardiac arrest. If not promptly rescued, the patient can die.

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Written by Xu Jun Hui
General Surgery
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Which department should I go to at the hospital for a tetanus shot?

Tetanus shots should be administered at a regular hospital in the emergency department. There are two types of tetanus injections: one that requires a skin test, called tetanus toxoid, and one that doesn't require a skin test, called tetanus immunoglobulin. It is generally recommended to get the tetanus shot within 24 hours of injury, and it is best to avoid alcohol before the injection. Drinking can cause dilation and reddening of the skin's capillaries, which can affect the results of the tetanus skin test. Tetanus is usually caused by the invasion of Clostridium tetani into the body, a type of anaerobic bacterium. Thus, for wounds that are small, deep, and heavily contaminated, such as with dirt, rust, or in cases of open fractures, anti-tetanus treatment is essential, and a tetanus shot can be administered in the hospital's emergency department.

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Written by Zhang Da Wei
General Surgery
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Does tetanus cause fever in its early stages?

Tetanus is actually a disease caused by the tetanus bacillus, generally entering the body after mucous membrane damage. In the early stages of tetanus, there usually are no fever symptoms. Fever typically appears in the middle to late stages. Generally, it is preceded by symptoms like episodic muscle spasms or tonic spasms. During this period, the incubation period can be about one week. In this time, the patient may experience symptoms such as general fatigue, headaches, and dizziness. Under circumstances where infection is likely, it is crucial to administer tetanus antitoxin promptly to effectively prevent the disease. Since the disease's morbidity and danger increase significantly in its middle to late stages, and the likelihood of death is also relatively high.

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Written by Zhang Peng
General Surgery
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How long does tetanus antibody last?

The duration of tetanus antibodies varies under two scenarios. The first is passive immunity, which is achieved through injections such as tetanus antitoxin or tetanus immunoglobulin. The duration of immunity provided by these injections is relatively short. Typically, tetanus antitoxin lasts about four days, while tetanus immunoglobulin can last up to three weeks. After this period, the levels of antibodies gradually decrease, and the body may no longer be protected. Therefore, a single application of tetanus antitoxin or immunoglobulin does not provide long-lasting immunity. The second scenario involves antibodies produced by active immunity, generally through the injection of a vaccine made from attenuated tetanus bacilli. Antibodies usually start to develop about ten days after vaccination, with levels gradually increasing over two to three months and remaining high. This type of immunity lasts up to about ten years, but it is not lifelong. Regular boosters, guided by relevant tests, are required to maintain immunity.