Pediatric diarrhea primarily refers to changes in the frequency and characteristics of stool due to various causes. Active treatment is necessary for pediatric diarrhea, starting with infection control as the initial step in pharmacological treatment. If the diarrhea is confirmed to be caused by a bacterial infection, antibiotics should be used under the guidance of a hospital physician. Secondly, treatment of the intestinal microecosystem is essential, commonly involving the administration of probiotics to children to help restore the ecological balance of normal intestinal flora, inhibiting the colonization and invasion of various pathogens, thus treating the diarrhea. Additionally, intestinal mucosal protectants, such as commonly used smectite powder, can enhance the barrier functions of the intestine to prevent pathogenic microorganisms from attacking the intestine and intestinal mucosa. Another treatment is anti-secretory therapy, frequently using racemic cadozetrack, along with zinc supplementation. Zinc supplements should be given to children with acute diarrhea to promote the repair of intestinal mucosa and prevent future mucosal damage, which can lead to acute diarrhea.