Secondary infertility refers to a condition where a person is unable to become pregnant or carry a pregnancy to term following the birth of one or more biological children.

Written by Zhang Xiu Rong
Obstetrics and Gynecology
Updated on January 01, 2025
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Infertility is divided into primary infertility and secondary infertility. Primary infertility refers to never having been pregnant before, which is called primary infertility. Secondary infertility generally occurs in individuals who have had children or a history of miscarriage and have been unable to conceive again after trying for a year, thus constituting secondary infertility. It is essential for those with secondary infertility to undergo relevant fertility tests at a hospital. Typically, the clinical evaluation includes a semen analysis for the male partner, and for the female partner, tests such as Mycoplasma and Chlamydia detection, endocrine examinations, immunological tests, and assessments for fallopian tube patency and related endocrine tests. Generally, through these tests, the cause of secondary infertility can be identified, and treatment can be tailored based on the results. In cases of secondary infertility, the vast majority can achieve conception through targeted treatment.

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Can a cold uterus and overall body coldness lead to infertility?

Cold womb and overall bodily coldness can lead to infertility. Since a cold womb and overall coldness can cause menstrual irregularities, scanty menstrual flow, and painful menstruation, it is essential to expel the cold promptly. Firstly, drinking ginger water can warm the womb and dispel coldness, or drinking brown sugar water can also effectively regulate these conditions. Moreover, it is important to avoid cold and raw foods in your diet; instead, focus on consuming warm foods and drink plenty of plain hot water to accelerate the healing process.

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Will infertility cause amenorrhea?

The WHO defines infertility as the condition when both the husband and wife have no desire to remain childless. If they cohabit for more than a year with normal sexual relations and without taking any contraceptive measures and still fail to conceive, they are diagnosed with infertility. Infertility and irregular menstruation are not related, nor does infertility lead to amenorrhea. Amenorrhea or irregular menstruation is due to endocrine reasons. This requires blood tests for six hormone levels, thyroid function, and some endocrine metabolism indicators. These can cause difficulty in conceiving and lead to ovulation disorders. Infertility does not cause amenorrhea, but if amenorrhea occurs, it might affect pregnancy and lead to infertility. This is the relationship between them.

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Precautions for Infertility Examination

Infertility examinations primarily involve tests for both men and women. For men, the examination includes a semen analysis which requires abstinence for 2-7 days. Semen should be collected through masturbation, using a specialized semen collection cup provided by the laboratory. Ordinary condoms should not be used for semen collection. After collection, the semen must be kept warm and promptly delivered back to the laboratory. For women, the examinations include several aspects. First, during the menstrual period, blood is drawn on an empty stomach between the 2nd and 4th days to check hormone levels, and an ultrasound is used to assess the baseline state of the ovaries. Second, between the 3rd and 7th days after the menstrual period ends, when sexual intercourse is prohibited, tests are conducted to examine the uterus and fallopian tubes. These may include hysterosalpingography, hysteroscopy, or laparoscopy to evaluate the condition of the fallopian tubes. Third, monitoring ovulation with ultrasound begins from the 8th to 10th day of the menstrual cycle, tracking the development of follicles and the uterine lining until the follicle matures and ovulation occurs.

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Infertility is a condition.

Infertility refers to the condition where, after a couple has married and cohabited for more than a year, despite having regular sexual intercourse without any contraception, they are unable to conceive naturally. There are many factors that can cause infertility, including factors related to the male, the female, or both. Male factors account for about 40% of infertility cases, female factors account for about 50%, and combined factors account for about 10%. Female infertility includes ovarian infertility, fallopian tube infertility, uterine infertility, cervical infertility, vaginal infertility, immunological infertility, and more.

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Causes of infertility

Infertility may be due to factors involving either the male or the female. The main causes of female infertility include ovulatory disorders and fallopian tube factors. Ovulatory disorders may result from dysfunction in ovulation, such as changes in the hypothalamic-pituitary-ovarian axis, as well as ovarian diseases, with polycystic ovary syndrome being the most common condition that could lead to ovulatory issues. Fallopian tube factors include blockages or inefficiencies, which can also cause infertility in women. Uterine factors can also lead to infertility, including abnormalities of the uterus, inflammation of the endometrium, polyps in the endometrium, and intrauterine adhesions, all of which can affect the implantation of the fertilized egg and cause infertility. Abnormal cervical mucus secretion, cervical inflammation, and an unusual immune environment in cervical mucus that affects sperm passage can also lead to infertility. Male infertility factors primarily include disorders of sperm production and sperm delivery, which may manifest as abnormalities in semen, shown by the absence of sperm, weak sperm, or low sperm count, all contributing to infertility. Additionally, sexual dysfunctions such as premature ejaculation, anejaculation, and erectile dysfunction can also result in male infertility.