Does neonatal jaundice cause fever?

Written by Li Jiao Yan
Neonatology
Updated on September 22, 2024
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Fever in newborns with simple jaundice is relatively rare. If a newborn has jaundice accompanied by fever, it is important to be vigilant for the possibility of sepsis. Since the symptoms of sepsis in newborns are atypical and non-specific, it is essential to take this seriously. It is recommended that parents promptly take the child to the hospital for examination. A blood culture should be performed to determine if sepsis is present. If the jaundice is excessively high, active phototherapy may be necessary to reduce the bilirubin levels.

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Written by Li Jiao Yan
Neonatology
1min 40sec home-news-image

What to do with neonatal jaundice?

Neonatal jaundice is the most common disease in newborns, mainly characterized by yellowing of the skin. Generally, normal babies also exhibit jaundice, but this is a type of physiological jaundice. If the baby's jaundice appears early, such as within twenty-four hours, or if the jaundice progresses rapidly with significantly rising jaundice levels, or if it is particularly severe, or if the jaundice lasts for a long duration, or if the jaundice recurs after fading, these are considered pathological jaundice. It is generally advised for pathological jaundice to consult a neonatal specialist for a detailed examination of the baby to determine whether treatment intervention is necessary. If the jaundice is severe and parents are worried, it is recommended to go to the hospital in a timely manner, as hospitalization for treatment may be needed. If the jaundice level is too high and there are some pathological factors, and parents are unable to observe the baby well and the baby's condition is not good, and the jaundice continues to rise, it could potentially progress to the brain, leading to bilirubin encephalopathy, which is a serious complication. Therefore, high jaundice levels still require timely intervention. If the jaundice is at its peak, it is recommended to test for jaundice daily, as timely intervention when jaundice levels are high can prevent serious complications.

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Written by Li Jiao Yan
Neonatology
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Causes of neonatal jaundice

Neonatal jaundice is generally divided into physiological jaundice and pathological jaundice. Physiological jaundice is usually considered a normal phenomenon, where the baby's jaundice can naturally recede without much impact on the baby. If it is pathological jaundice, it means that the jaundice level is high, indicating a pathological condition. Pathological jaundice can be further divided into several types, the most common being elevated direct bilirubin and elevated indirect bilirubin, each with different causes. Common causes of jaundice include increased indirect bilirubin due to infections, hemolysis, and mother-infant blood type incompatibility, such as ABO incompatibility where the mother is type O and the baby is not, or the mother has HR-negative blood and the baby has HR-positive blood. Other factors include reduced thyroid function, enzyme deficiencies such as G6PD deficiency, various types of bleeding like gastrointestinal bleeding, intracranial bleeding, or asphyxia at birth. Conditions like hypoxia or acidosis in the baby can also lead to increased jaundice. Additionally, liver function damage due to viral infections like hepatitis B, cytomegalovirus, and other infectious diseases such as syphilis, as well as other viruses like rubella virus and herpes virus can elevate jaundice levels. Developmental abnormalities of the biliary tract, commonly biliary atresia or congenital bile duct dilation, can cause elevated conjugated bilirubin levels. The causes of jaundice are complex, and some causes might remain unidentified. However, if the baby's general condition is good and the jaundice is manageable, it generally does not affect the baby. If jaundice levels are high, it is advised to visit a hospital where doctors can conduct relevant tests based on the baby's specific condition to determine if treatment is needed.

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Written by Li Jiao Yan
Neonatology
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Neonatal jaundice symptoms

Neonatal jaundice is most commonly seen in the skin and mucous membranes, and the sclera, or what we refer to as the eyes, presenting with a yellow discoloration of the white part. The most common symptom is yellowing of the skin. There may also be other symptoms such as crying and restlessness, fever, or rapid and irregular breathing. Some babies might sleep longer than usual, have difficulty feeding, or experience issues with bowel movements, such as a significant decrease in stool frequency or a reduction in urine output. These could be accompanying symptoms of neonatal jaundice. Each baby presents differently with jaundice; more accompanying symptoms often indicate a more severe condition. If the jaundice is limited to skin discoloration without other significant symptoms, it may indicate an early stage of the condition. Generally, if the jaundice is pronounced, it is considered pathological jaundice, and it is advisable to go to the hospital. A pediatric specialist can conduct relevant examinations and decide if immediate intervention and treatment are necessary.

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Written by Li Jiao Yan
Neonatology
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Neonatal jaundice peak period is a few days.

Neonatal jaundice is one of the common symptoms during the neonatal period; it could be a normal physiological phenomenon, or it might be an external manifestation of certain diseases. Typically, physiological jaundice appears two to three days after birth, reaches its peak within four to five days in full-term infants, and may appear sooner and be more severe in preterm infants due to their less mature liver function. The peak period lasts longer for preterm babies; generally, in full-term infants, jaundice usually starts declining about a week later, subsiding around ten days, generally not lasting more than two weeks.

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Written by Yao Li Qin
Pediatrics
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How to deal with neonatal jaundice hemolysis?

Neonatal hemolytic disease refers to alloimmune hemolysis caused by maternal-fetal blood type incompatibility, commonly seen in life with A, B, O blood type mismatches, and Rh blood type mismatch is less common. Once neonatal hemolytic disease is diagnosed, aggressive treatment must be pursued. Initially, phototherapy treatment is recommended, commonly referred to as blue light therapy. Additionally, medication therapy for the child is necessary, frequently involving albumin and intravenous immunoglobulin, along with the use of sodium bicarbonate to correct acidosis. If the aforementioned treatments do not yield satisfactory results, blood exchange treatment should be considered for the child. This mainly involves removing free antibodies and sensitized red blood cells from the blood, thereby alleviating hemolysis and ultimately achieving therapeutic goals. (Please use medication under the guidance of a doctor.)