Neurodermatitis, also known as chronic simple lichen, is a common chronic inflammatory skin disease characterized by episodic severe itching and lichenoid skin changes due to neurofunctional disorders. Clinically, topical medications are chosen based on the characteristics, location, and type of skin lesions. Commonly used topical medications include corticosteroid ointments, tar-based moisturizing ointments, and anti-itch ointments. From the perspective of Chinese medicine, garlic can be used topically to kill insects and relieve itching, but it has strong irritants that can cause skin redness, blisters, and itching. Therefore, we do not recommend patients to use garlic to treat neurodermatitis.