Neurodermatitis, also known as simple lichen, commonly occurs on the eyelids, elbows, neck, and sacral areas. It exhibits recurrent symptoms such as skin lesions and itching. It is necessary to enhance skin moisturization, avoid excessive irritants such as friction, and provide anti-inflammatory symptomatic treatment. Oral medications such as levocetirizine tablets, moisturizing and anti-itching capsules, compound glycyrrhizin tablets, Guweisupian tablets, or Duluoping tablets, along with topical application of tacrolimus ointment, or early use of potent steroids such as halometasone cream or betamethasone valerate cream, can control the symptoms of skin lesions. However, steroid creams should not be used for prolonged periods as they can cause side effects including skin atrophy and hypertrichosis.