How is cervical cancer checked?

Written by Li Lin
Obstetrics and Gynecology
Updated on January 30, 2025
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Cervical cancer screening begins with testing for the human papillomavirus (HPV) and a cervical cytology smear test. If abnormalities are found in these tests, a colposcopy examination is needed. Under colposcopy, suspicious cancerous areas are selected for a cervical biopsy, and the cervical tissue is sent for pathological sections. Based on the results of the pathology sections, it is determined whether the condition is a precancerous lesion of the cervix or cervical cancer. If cervical cancer is present, a clinical doctor must perform a gynecological internal examination to determine the stage of the cervical cancer, and then choose a treatment plan.

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Oncology
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Causes of Cervical Cancer

The causes of cervical cancer include: The first point is infection by the human papillomavirus (HPV), particularly persistent infection with high-risk types, which is the basic cause of precancerous lesions and cervical cancer. The second point is that DNA from HPV is not detected in the tumor tissues of a minority of cases, especially among some older patients. Epidemiology shows that early childbirth and multiparity are closely related to the occurrence of cervical cancer. With an increasing number of childbirths, the risk of cervical cancer also increases. This correlation might be due to the trauma to the cervix during childbirth and changes to the endocrine and nutritional states during pregnancy.

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Written by Shen Li Wen
Obstetrics and Gynecology
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Does cervical cancer hurt?

Women with cervical cancer usually have no specific clinical symptoms in the early stages of the disease. As the tumor increases in size, some women may experience contact bleeding, which occurs after sexual intercourse. As the cancer grows and compresses the surrounding tissues, it can cause local feelings of distension and even pain. In some women, the spread of cancer cells can compress nerves in the pelvic area, also causing localized pain. However, this generally occurs in the later stages of the disease. By this advanced stage, the pain caused by the tumor cannot be alleviated by ordinary analgesics, and drugs like morphine are usually required for pain relief. (Please use medication under the guidance of a doctor.)

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Written by Gong Chun
Oncology
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Cervical cancer screening

For the examination of cervical cancer, it should be based on medical history and clinical manifestations, especially for people with contact vaginal bleeding, a detailed general examination and gynecological examination should be conducted, and an examination of cervical biopsy tissue is needed for diagnosis. What specific examinations are there? There are cervical scrape cytology tests, iodine tests, colposcopy, examination of cervical and cervical canal tissue, as well as post-surgical cervical conization, and examination of postoperative specimens. Therefore, there are indeed many examinations, including some radiological assessments such as enhanced CT, PADCT, MRI, and other such tests.

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Written by Xu Xiao Ming
Obstetrics and Gynecology
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Causes of cervical cancer

There are several causes of cervical cancer, such as having multiple sexual partners, premature birth, smoking, and early sexual activity, all of which could lead to cervical cancer. However, the main cause of cervical cancer is infection with HPV, the human papillomavirus. It has been scientifically proven that cervical cancer is caused by HPV infection. Therefore, this viral infection is the primary cause of cervical cancer. It is recommended that women of childbearing age undergo cervical cancer screening to check for any abnormalities in the cervix.

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Written by Gong Chun
Oncology
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Cervical Cancer Staging Criteria

For the staging of cervical cancer, the staging criteria of the International Federation of Gynecology and Obstetrics (FIGO) are now adopted. Staging should be done before treatment, and since the FIGO staging of the cervix mainly relies on the examination of the pelvis, it is emphasized that the pelvic examination must be performed by two senior gynecologic oncologists. The staging primarily involves assessing the size of the cervical lesion, particularly the measurement of endophytic tumors, parametrial tissue infiltration, and the status of pelvic lymph nodes. However, these stages mainly rely on radiological examinations, primarily magnetic resonance imaging (MRI), to provide objective data for staging.