Cervical Cancer Staging Criteria

Written by Gong Chun
Oncology
Updated on September 04, 2024
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For the staging of cervical cancer, the staging criteria of the International Federation of Gynecology and Obstetrics (FIGO) are now adopted. Staging should be done before treatment, and since the FIGO staging of the cervix mainly relies on the examination of the pelvis, it is emphasized that the pelvic examination must be performed by two senior gynecologic oncologists. The staging primarily involves assessing the size of the cervical lesion, particularly the measurement of endophytic tumors, parametrial tissue infiltration, and the status of pelvic lymph nodes. However, these stages mainly rely on radiological examinations, primarily magnetic resonance imaging (MRI), to provide objective data for staging.

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How long does it take for cervical cancer to develop?

Cervical cancer generally forms beginning with an infection of human papillomavirus (HPV), and it usually takes five to ten years to develop into cervical cancer. The vast majority of cervical cancer cases are caused by contact with HPV. If this virus continues to replicate in the body, it typically progresses to cervical cancer over a period of five to ten years. Therefore, cervical cancer screening is crucial for women. If regular check-ups are performed annually during this period, it is possible to halt the progression to cervical cancer and its precursors. Cervical cancer screening generally includes routine TCT (ThinPrep Cytologic Test) and HPV testing. These two tests can preliminarily screen for cervical cancer and precancerous conditions. If any abnormalities are detected, it is essential to undergo a colposcopic biopsy at a hospital, as biopsy is the gold standard for diagnosis.

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Does cervical cancer cause anemia in the early stages?

Cervical cancer is one of the common malignant tumors in gynecology, and a small number of patients with cervical cancer may experience anemia in the early stages. This is because the main clinical symptoms of early-stage cervical cancer patients are mainly vaginal bleeding or vaginal discharge. As the amount of vaginal bleeding in patients with cervical cancer is not significantly related to the stage of the cancer, some patients in the early stages of cervical cancer may have a large amount of vaginal bleeding, which can lead to mild anemia. In some cases, patients may experience severe bleeding, which can lead to anemia-induced shock. For patients with cervical cancer, in addition to vaginal bleeding, some patients may also experience an increase in vaginal secretions and vaginal discharge. Young women may also experience an extension of the menstrual cycle and an increase in menstrual volume, all of which can cause anemia in patients clinically.

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Early symptoms of cervical cancer

The most common early symptom of cervical cancer may be contact bleeding, including vaginal bleeding after intercourse. However, not many patients exhibit these symptoms. Many patients do not show any symptoms, but there are some pathological changes on the cervix. Therefore, it is recommended that women who are sexually active should undergo regular early screening for cervical cancer, including HPV, TCT, and colposcopy examinations. Regular checks can determine whether there are indeed pathological changes on the cervix. This is also a preventive measure for women, and the screening is highly efficient at detecting early pathological changes in the cervix.

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Can a cervical biopsy detect cervical cancer?

Cervical biopsy can detect cervical cancer as long as the altered tissue is collected. However, some people have a type 3 transformation zone in the cervix, making it difficult to obtain the altered tissue, and in these cases, cervical scraping is needed. Therefore, it is best to perform the biopsy under colposcopic examination and conduct a cervical canal scraping at the same time. If there is cervical cancer, it can be detected, and generally, it will not be missed.

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Cervical cancer indicators

The main indicators of cervical cancer are still the examination of the cervix and cervical canal tissues. There are obvious cancerous changes, and under the microscope pathological sections can show tendencies of cell carcinogenesis, or already developed cancer. The second is the cytological examination of cervical scrapings, which detects the presence of cancer cells. The third is the iodine test, where areas that do not stain after iodine staining indicate a lack of glycogen in the epithelium, suggesting possible lesions. The fourth is colposcopy, which may reveal suspicious cancerous areas, allowing for biopsy to confirm cancer cells. The fifth includes ultrasound, CT, MRI, etc., which can detect mass occupying lesions, all of which are indicators of cervical cancer. Of course, abnormalities in tumor markers are also considered, but the main reliance is still on the indicators from pathological examinations to determine if it's cervical cancer.