Causes of cervical cancer

Written by Gong Chun
Oncology
Updated on September 03, 2024
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The causes of cervical cancer are particularly associated with human papillomavirus (HPV) infection. The primary causes that can lead to precancerous lesions and cervical cancer itself, in a minority of cases, do not detect HPV DNA, especially in older patients. Epidemiological studies show that early childbirth and multiple childbirths are highly related to the incidence of cervical cancer; as the number of childbirths increases, the risk of cervical cancer also increases. Smoking can suppress the body's immune function and may promote cancer development. Men who have had penile cancer, prostate cancer, or previous cervical cancer are at high risk; therefore, women who have contact with high-risk men are also more susceptible to cervical cancer.

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Can a cervical biopsy detect cervical cancer?

Cervical biopsy can detect cervical cancer as long as the altered tissue is collected. However, some people have a type 3 transformation zone in the cervix, making it difficult to obtain the altered tissue, and in these cases, cervical scraping is needed. Therefore, it is best to perform the biopsy under colposcopic examination and conduct a cervical canal scraping at the same time. If there is cervical cancer, it can be detected, and generally, it will not be missed.

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Cervical cancer indicators

The main indicators of cervical cancer are still the examination of the cervix and cervical canal tissues. There are obvious cancerous changes, and under the microscope pathological sections can show tendencies of cell carcinogenesis, or already developed cancer. The second is the cytological examination of cervical scrapings, which detects the presence of cancer cells. The third is the iodine test, where areas that do not stain after iodine staining indicate a lack of glycogen in the epithelium, suggesting possible lesions. The fourth is colposcopy, which may reveal suspicious cancerous areas, allowing for biopsy to confirm cancer cells. The fifth includes ultrasound, CT, MRI, etc., which can detect mass occupying lesions, all of which are indicators of cervical cancer. Of course, abnormalities in tumor markers are also considered, but the main reliance is still on the indicators from pathological examinations to determine if it's cervical cancer.

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Oncology
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Treatment of Cervical Cancer

The treatment principle of cervical cancer primarily focuses on surgical and radiotherapy, supplemented by chemotherapy and other comprehensive treatment plans. Therefore, it should be based on clinical staging and the specific condition of the patient, such as age and physical health, combined with the overall situation, as well as considering the level of technology and equipment conditions to develop a suitable treatment plan. Nowadays, emphasis is placed on personalized treatment and initial treatment. Cervical cancer treatment primarily involves surgery, including extensive hysterectomy and extensive cervical excision, where choosing the appropriate surgical method is key. Post-surgery, radiotherapy can be combined, and for those unsuitable for surgery, preoperative radiotherapy is an option. Additionally, preoperative or postoperative adjuvant chemotherapy can also be considered.

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Cervical cancer symptoms

Cervical cancer generally has no symptoms in its early stages. In advanced stages, symptoms become more obvious. In the early stages, signs may include increased vaginal discharge, bleeding after sexual intercourse, or discharge containing blood streaks, typically without abdominal pain. In advanced stages, there might be irregular vaginal bleeding or heavy bleeding, and sometimes the secretions may appear like rice-wash water. If an infection occurs, there can be a foul smell, and pain in the lower abdomen may be felt, indicating the cancer has progressed to a late stage. Therefore, if there is an increase in discharge or bleeding after intercourse during the early stages, it is crucial to promptly visit a hospital for examination.

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Written by Gong Chun
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Cervical cancer treatment

For the treatment of cervical cancer, it should be based on the patient's physical condition, nutritional status, pathological staging, and pathological type to develop a comprehensive treatment plan, rather than a general, single approach. The treatment principle for cervical cancer mainly involves surgery and radiotherapy, supported by a comprehensive treatment plan that includes chemotherapy. However, the treatment plan should be based on clinical staging, age, overall health, and consider the level of technology and equipment available to formulate a suitable treatment plan. It is important to focus on individualized treatment and the method of initial treatment. Therefore, each person is different, and treatments vary from person to person and disease to disease.