How to treat chronic atrophic gastritis with intestinal metaplasia?

Written by Si Li Li
Gastroenterology
Updated on January 23, 2025
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The treatment of chronic atrophic gastritis with intestinal metaplasia mainly includes the following aspects:

The first is general treatment. Firstly, the diet should be light and easily digestible, avoiding spicy, stimulating, fried, grilled, cold, and sweet foods. It is important to exercise regularly and avoid emotions such as anxiety and depression.

The second is the treatment against Helicobacter pylori, including a proton pump inhibitor plus two antibiotics, and a bismuth agent, with a treatment course of 14 days. Additionally, medications that promote gastric motility and protect the gastric mucosa are used.

The fourth involves endoscopic treatments, including endoscopic APC treatment or endoscopic mucosal resection.

The fifth, combining traditional Chinese medicine, differentiating syndrome treatments and oral herbal medicines, can also achieve good effects.

Other Voices

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Can people with atrophic gastritis drink honey water?

Patients with atrophic gastritis can drink honey water. Patients with atrophic gastritis need to be careful with their diet by avoiding spicy, irritating foods, as well as overly sour, overly spicy, overly salty foods, and coarse foods. For patients with atrophic gastritis, it is important to eat regularly and in moderate amounts, opting for smaller, more frequent meals, and avoiding binge eating. Since honey water does not fall into the above categories of foods and is not considered spicy, patients with atrophic gastritis can drink honey water. However, it is also important to avoid drinking too much at once; drinking a moderate amount is fine.

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Atrophic gastritis with intestinal metaplasia what medicine to take

Chronic atrophic gastritis with intestinal metaplasia often arises from untreated chronic superficial gastritis, primarily due to Helicobacter pylori infection. Therefore, it is essential to first check for Helicobacter pylori infection. If an infection is present, quadruple therapy is generally used to eradicate the bacteria, which may improve the atrophy. If there is no Helicobacter pylori infection, treatment mainly involves protecting the gastric mucosa. While there are no specific Western medicines for this, traditional Chinese medicine and a differential diagnosis approach often yield good results. Regular follow-ups are also important. (Specific medications should be used under the guidance of a doctor.)

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The difference between superficial gastritis and atrophic gastritis.

Chronic superficial gastritis and atrophic gastritis are both types of chronic gastritis. Chronic superficial gastritis refers to the condition where there is no atrophy of the gastric glands in the gastric mucosa, while atrophic gastritis involves atrophy of the gastric glands in the gastric mucosa. Gastroscope examination can confirm the diagnosis; if gastric gland atrophy is observed under the gastroscope, a biopsy and histopathological examination can definitively diagnose atrophic gastritis. In contrast, superficial gastritis primarily shows symptoms of mucosal hyperemia, edema, or erosion under gastroscope examination. The symptoms of both conditions are similar, including upper abdominal distension, belching, acid reflux, nausea, and vomiting. As for treatment, superficial gastritis primarily involves acid suppression, gastric protection, and promoting gastric motility, while the treatment for atrophic gastritis includes targeting Helicobacter pylori, along with acid suppression and gastric protection. The prognosis for superficial gastritis is relatively good, whereas treating atrophic gastritis is more challenging and it carries a higher risk of malignancy transformation.

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Is atrophic gastritis of the gastric antrum serious?

Atrophic gastritis is a chronic gastric disease characterized by repeated damage to the gastric mucosal epithelium, leading to the atrophy of the intrinsic glands, with or without intestinal metaplasia or pseudopyloric gland metaplasia. The main cause of this disease is infection by Helicobacter pylori. Symptoms primarily include upper abdominal distension, belching, acid reflux, early satiety, nausea, etc. Some patients may experience symptoms such as weight loss, fatigue, memory loss, anxiety, and depression. The main treatment involves eradicating Helicobacter pylori, suppressing acid production, and using gastric mucosal protectants and prokinetic agents. The majority of patients have Helicobacter pylori-related gastritis, which after chronic inflammation (chronic non-atrophic gastritis) can lead to atrophic gastritis, followed by intestinal metaplasia or dysplasia, and eventually may progress to gastric cancer.

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How long does it take to treat atrophic gastritis with erosion?

Atrophic gastritis with erosion is a type of chronic gastritis and has a lengthy course of disease. Through treatment, the erosions may heal within six to eight weeks. However, reversing the atrophy of the gastric mucosa is a long-term and slow process, and there are no specific effective drugs clinically available. Some traditional Chinese medicines and proprietary Chinese medicines may be effective, but it typically takes at least six months. Therefore, the duration required to treat atrophic gastritis with erosion varies from person to person, depending on individual differences.