Is atrophic gastritis of the gastric antrum serious?

Written by Si Li Li
Gastroenterology
Updated on February 03, 2025
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Atrophic gastritis is a chronic gastric disease characterized by repeated damage to the gastric mucosal epithelium, leading to the atrophy of the intrinsic glands, with or without intestinal metaplasia or pseudopyloric gland metaplasia. The main cause of this disease is infection by Helicobacter pylori. Symptoms primarily include upper abdominal distension, belching, acid reflux, early satiety, nausea, etc. Some patients may experience symptoms such as weight loss, fatigue, memory loss, anxiety, and depression. The main treatment involves eradicating Helicobacter pylori, suppressing acid production, and using gastric mucosal protectants and prokinetic agents. The majority of patients have Helicobacter pylori-related gastritis, which after chronic inflammation (chronic non-atrophic gastritis) can lead to atrophic gastritis, followed by intestinal metaplasia or dysplasia, and eventually may progress to gastric cancer.

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Written by Wu Hai Wu
Gastroenterology
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What should I do if atrophic gastritis causes severe weight loss?

Patients with atrophic gastritis should be highly attentive if they experience significant weight loss and should receive standardized traditional treatments. Additionally, dietary habits also require careful attention; it is important to quit smoking and drinking alcohol, and to avoid using medications that damage the gastric mucosa, such as nonsteroidal anti-inflammatory drugs and steroids. Furthermore, eating habits should be regular, avoiding binge eating and foods that are too salty, spicy, or that are fried or deep-fried. Active treatment should also be directed against Helicobacter pylori, utilizing medications that protect the gastric mucosa, enhance its resistance to gastric acid, and improve the regenerative ability of gastric mucosal cells. Medications that inhibit bile reflux and improve gastric motility can also be employed.

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Written by Wu Peng
Gastroenterology
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Chronic atrophic gastritis is what kind of condition?

Chronic atrophic gastritis is a digestive system disease characterized by atrophy of the intrinsic gastric glands. It is commonly seen in middle-aged and elderly people. Clinically, it mainly manifests as loss of appetite, nausea, belching, heartburn, and continuous or intermittent bloating and dull pain in the upper abdomen. A minority of patients may experience upper gastrointestinal bleeding, weight loss, anemia, and malnutrition, with incidence rates increasing significantly with age. Chronic atrophic gastritis can be divided into autoimmune gastritis and multifocal atrophic gastritis, also referred to as Type A gastritis and Type B gastritis, respectively. Gastric mucosal biopsy is a reliable method for its diagnosis.

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Written by Jiang Guo Ming
Gastroenterology
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Difference between atrophic gastritis and non-atrophic gastritis

Chronic gastritis includes two types: chronic non-atrophic gastritis and chronic atrophic gastritis. The symptoms of both can be similar, such as upper abdominal pain, bloating, nausea, vomiting, acid reflux, and heartburn. Chronic atrophic gastritis tends to be more severe than non-atrophic gastritis. Over the long term, atrophic gastritis may lead to symptoms like fatigue, weight loss, loss of appetite, and even anemia. The main differentiation still requires gastroscopy and pathological examination. Under gastroscopy, chronic superficial gastritis mainly shows mucosal congestion and edema. In atrophic gastritis, due to gland atrophy, the submucosal blood vessels may appear as a net-like or petal-like pattern, and sometimes the mucosa may become granular. Pathological examinations can further clarify the diagnosis.

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Written by Si Li Li
Gastroenterology
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Can atrophic gastritis and gastric ulcers eat sweet potatoes?

Patients with atrophic gastritis and gastric ulcers should not eat sweet potatoes. Common symptoms for patients with atrophic gastritis and gastric ulcers include upper abdominal distension and pain, belching, acid reflux, nausea, vomiting, poor appetite, indigestion, and heartburn. After a clear diagnosis, standardized medication treatment is required. Additionally, it is essential for these patients to quit smoking and drinking alcohol; they should not drink strong tea or coffee. Foods that are rich, greasy, spicy, fried, grilled, cold, sweet, along with milk, soy milk, glutinous rice, and sweet potatoes are also not recommended. For example, sweet potatoes are difficult to digest and can increase gastric acid secretion, which further irritates the gastric mucosa and aggravates these two diseases. Therefore, patients with atrophic gastritis and gastric ulcers should not eat sweet potatoes.

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Written by Si Li Li
Gastroenterology
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Is atrophic gastritis easy to treat?

Atrophic gastritis is a type of chronic gastritis characterized by the atrophy of gastric mucosal glands. It carries a certain risk of becoming cancerous. The main symptoms include upper abdominal pain, postprandial fullness, heartburn, indigestion, belching, and acid reflux. Gastroscope examination reveals atrophy of the gastric glands, and a biopsy is needed for a pathological examination to confirm the diagnosis of chronic atrophic gastritis. In terms of treatment, the first step is to eradicate Helicobacter pylori, which includes a regimen of one proton pump inhibitor, two antibiotics, and one bismuth agent, lasting for 14 days. This is followed by acid suppression and mucosal repair treatments. Additionally, the treatment with traditional Chinese medicine plays a significant role in managing atrophic gastritis. This condition is challenging to treat, has poor outcomes, is prone to relapse, and carries a risk of cancer transformation.