Atrophic gastritis with intestinal metaplasia what medicine to take

Written by Jiang Guo Ming
Gastroenterology
Updated on September 05, 2024
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Chronic atrophic gastritis with intestinal metaplasia often arises from untreated chronic superficial gastritis, primarily due to Helicobacter pylori infection. Therefore, it is essential to first check for Helicobacter pylori infection. If an infection is present, quadruple therapy is generally used to eradicate the bacteria, which may improve the atrophy. If there is no Helicobacter pylori infection, treatment mainly involves protecting the gastric mucosa. While there are no specific Western medicines for this, traditional Chinese medicine and a differential diagnosis approach often yield good results. Regular follow-ups are also important. (Specific medications should be used under the guidance of a doctor.)

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Written by Wu Peng
Gastroenterology
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Chronic atrophic gastritis is what kind of condition?

Chronic atrophic gastritis is a digestive system disease characterized by atrophy of the intrinsic gastric glands. It is commonly seen in middle-aged and elderly people. Clinically, it mainly manifests as loss of appetite, nausea, belching, heartburn, and continuous or intermittent bloating and dull pain in the upper abdomen. A minority of patients may experience upper gastrointestinal bleeding, weight loss, anemia, and malnutrition, with incidence rates increasing significantly with age. Chronic atrophic gastritis can be divided into autoimmune gastritis and multifocal atrophic gastritis, also referred to as Type A gastritis and Type B gastritis, respectively. Gastric mucosal biopsy is a reliable method for its diagnosis.

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Written by Ren Zheng Xin
Gastroenterology
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What are the symptoms of atrophic gastritis?

Atrophic gastritis, also known as body-type gastritis, is mainly caused by Helicobacter pylori infection leading to atrophy of the gastric mucosa. Under microscopy, twisted blood vessels and alternating red and white mucosa can be seen. The main symptoms include nausea, vomiting, and decreased appetite. A reduction in parietal cells can lead to decreased secretion of intrinsic factor, thereby causing anemia with red blood cells. If atrophic gastritis is accompanied by ulcers, it can cause severe abdominal pain and bloody stools. It is important to adjust the diet, eat more soft and easily digestible foods, and consume fewer raw, cold, and spicy foods.

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Written by Si Li Li
Gastroenterology
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Chronic non-atrophic gastritis with bile reflux treatment

Chronic non-atrophic gastritis with bile reflux is mainly characterized by symptoms such as upper abdominal distension, belching, acid reflux, nausea, vomiting, poor appetite, and indigestion. A diagnosis can be made if bile reflux into the stomach or bile patches on the stomach wall are observed during gastroscopy. A Carbon-14 breath test is also necessary to determine the presence of Helicobacter pylori infection. If the infection test is positive, a 14-day anti-Helicobacter pylori treatment is required. Additionally, treatment for chronic non-atrophic gastritis with bile reflux should include acid suppression, gastric protection, and promotion of gastric motility to protect the gastric mucosa, with a treatment duration of about four to six weeks. Bile reflux-associated chronic gastritis is primarily caused by poor gastric motility, thus increasing physical exercise is recommended as it can enhance gastric motility and improve the condition.

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Written by Si Li Li
Gastroenterology
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The symptoms of atrophic gastritis include:

The primary symptoms of atrophic gastritis include upper abdominal distension and pain, post-meal fullness, early satiety, belching, acid reflux, nausea, and vomiting. Some patients may also experience weight loss, fatigue, anxiety, depression, and forgetfulness. Additionally, some may suffer from dizziness, weakness, and pale complexion. If the gastric mucosa is eroded or even bleeding, it can lead to gastric bleeding and result in anemia. In terms of treatment, the primary approach is the eradication of Helicobacter pylori, using a regimen that includes a proton pump inhibitor, two types of antibiotics, and a bismuth agent. Additionally, treatments include acid suppression, gastric protection, and enhancing gastric motility. Traditional Chinese medicine and herbal treatments are also very important methods for treating atrophic gastritis.

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Written by Si Li Li
Gastroenterology
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How to treat chronic atrophic gastritis with intestinal metaplasia?

The treatment of chronic atrophic gastritis with intestinal metaplasia mainly includes the following aspects: The first is general treatment. Firstly, the diet should be light and easily digestible, avoiding spicy, stimulating, fried, grilled, cold, and sweet foods. It is important to exercise regularly and avoid emotions such as anxiety and depression. The second is the treatment against Helicobacter pylori, including a proton pump inhibitor plus two antibiotics, and a bismuth agent, with a treatment course of 14 days. Additionally, medications that promote gastric motility and protect the gastric mucosa are used. The fourth involves endoscopic treatments, including endoscopic APC treatment or endoscopic mucosal resection. The fifth, combining traditional Chinese medicine, differentiating syndrome treatments and oral herbal medicines, can also achieve good effects.