Atrophic gastritis with intestinal metaplasia what medicine to take

Written by Jiang Guo Ming
Gastroenterology
Updated on September 05, 2024
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Chronic atrophic gastritis with intestinal metaplasia often arises from untreated chronic superficial gastritis, primarily due to Helicobacter pylori infection. Therefore, it is essential to first check for Helicobacter pylori infection. If an infection is present, quadruple therapy is generally used to eradicate the bacteria, which may improve the atrophy. If there is no Helicobacter pylori infection, treatment mainly involves protecting the gastric mucosa. While there are no specific Western medicines for this, traditional Chinese medicine and a differential diagnosis approach often yield good results. Regular follow-ups are also important. (Specific medications should be used under the guidance of a doctor.)

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Written by Gong Chun
Oncology
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Can atrophic gastritis lead to gastric cancer?

The development of gastric cancer, particularly intestinal-type gastric cancer, is a multi-stage process influenced by various factors. Chronic atrophic gastritis is primarily characterized by the atrophy and reduction of gastric mucosal glands. Consequently, it often accompanies varying degrees of metaplasia in the gastrointestinal mucosal epithelium. Chronic atrophic gastritis features a reduction in B cells of the gastric glands, and the pH value of gastric juice may increase. Hence, the relationship between chronic atrophic gastritis and gastric cancer is significant, as it is considered a precancerous lesion. Therefore, if one has atrophic gastritis, it is crucial to seek timely medical treatment to prevent worsening of the condition.

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Written by Jiang Guo Ming
Gastroenterology
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Is nausea normal for atrophic gastritis?

Nausea is one of the common symptoms of gastrointestinal diseases, whether it is chronic superficial gastritis or atrophic gastritis. The occurrence of nausea usually indicates insufficient gastric motility. This condition is not considered normal, and targeted treatment is usually required depending on whether there is an infection with Helicobacter pylori. If there is an infection with Helicobacter pylori, it is first necessary to eradicate Helicobacter pylori. This generally involves quadruple therapy to eliminate the bacteria, accompanied by prokinetic agents, such as mosapride citrate. If there is no Helicobacter pylori infection, symptomatic treatment may suffice. For example, protecting the gastric mucosa and enhancing gastric motility, while also paying attention to daily dietary and lifestyle habits. (Note: The use of medications should be conducted under the guidance of a professional doctor.)

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Written by Jiang Guo Ming
Gastroenterology
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How to prevent and treat atrophic gastritis

Chronic gastritis includes two types: chronic non-atrophic gastritis and chronic atrophic gastritis. Chronic atrophic gastritis is generally more severe than chronic non-atrophic gastritis and usually accompanies intestinal metaplasia, which some refer to as a precancerous lesion. If chronic atrophic gastritis is present, formal medical treatment is necessary. Initially, it is advisable to check for Helicobacter pylori infection. If an Helicobacter pylori infection is found, timely eradication therapy is recommended, typically using quadruple therapy, which consists of a proton pump inhibitor, two types of antibiotics, and a bismuth agent. If there is no Helicobacter pylori infection, treatment generally focuses on symptomatic relief, such as protecting the gastric mucosa and enhancing gastric motility. Additionally, traditional Chinese medicine has shown satisfactory effects in treating chronic atrophic gastritis. It is also important to maintain good dietary and living habits, prefer light and easily digestible foods, and avoid raw, greasy, spicy, and irritating foods to help maintain a positive state of mind. Regular gastroscopy check-ups are necessary. (Medication should be taken under the guidance of a doctor.)

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Written by Wu Hai Wu
Gastroenterology
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What should I do if atrophic gastritis causes severe weight loss?

Patients with atrophic gastritis should be highly attentive if they experience significant weight loss and should receive standardized traditional treatments. Additionally, dietary habits also require careful attention; it is important to quit smoking and drinking alcohol, and to avoid using medications that damage the gastric mucosa, such as nonsteroidal anti-inflammatory drugs and steroids. Furthermore, eating habits should be regular, avoiding binge eating and foods that are too salty, spicy, or that are fried or deep-fried. Active treatment should also be directed against Helicobacter pylori, utilizing medications that protect the gastric mucosa, enhance its resistance to gastric acid, and improve the regenerative ability of gastric mucosal cells. Medications that inhibit bile reflux and improve gastric motility can also be employed.

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Written by Si Li Li
Gastroenterology
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Is chronic non-atrophic gastritis with erosion serious?

Common symptoms of chronic non-atrophic gastritis with erosion include upper abdominal bloating, belching, acid reflux, nausea, vomiting, poor appetite, indigestion, heartburn, etc. A gastroscopy can reveal symptoms like hyperemia, edema, and erosion on the gastric mucosa to diagnose chronic non-atrophic gastritis with erosion. It is also recommended to perform a Carbon-14 breath test to determine if there is an infection of Helicobacter pylori. If the infection is positive, a 14-day treatment for Helicobacter pylori is required, using a regimen of a proton pump inhibitor, two antibiotics, and a bismuth agent, with the course lasting 14 days. Additionally, treatment for chronic non-atrophic gastritis with erosion should include acid suppression, gastric protection, promoting gastric motility, and protecting the gastric mucosa, which typically requires about six weeks. With the above treatments, the disease can be cured.