Can atrophic gastritis with HP positive lead to cancer?

Written by Si Li Li

Gastroenterology

Updated on March 31, 2025

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Chronic atrophic gastritis has a certain risk of cancerous transformation. For patients with chronic atrophic gastritis, the first step in treatment is to administer anti-Helicobacter pylori therapy, which includes a proton pump inhibitor, two types of antibiotics, and a bismuth agent, with a treatment duration of 14 days. Additionally, treatments to suppress stomach acid, protect the stomach lining, promote gastric motility, and repair the stomach mucosa are necessary. Treatment methods also involve traditional Chinese medicine (TCM) diagnoses and oral administration of Chinese herbal medicine. External TCM treatments, such as thunder-fire moxibustion and moxibustion on the Zhongwan acupoint, or the acupoints of spleen-shu and stomach-shu on the back, which strengthen the spleen and benefit qi to nourish the stomach, can also play a significant role in treating this disease.

Other Voices

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Written by Jiang Guo Ming

Gastroenterology

1min 22sec

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How to prevent and treat atrophic gastritis

Chronic gastritis includes two types: chronic non-atrophic gastritis and chronic atrophic gastritis. Chronic atrophic gastritis is generally more severe than chronic non-atrophic gastritis and usually accompanies intestinal metaplasia, which some refer to as a precancerous lesion. If chronic atrophic gastritis is present, formal medical treatment is necessary. Initially, it is advisable to check for Helicobacter pylori infection. If an Helicobacter pylori infection is found, timely eradication therapy is recommended, typically using quadruple therapy, which consists of a proton pump inhibitor, two types of antibiotics, and a bismuth agent. If there is no Helicobacter pylori infection, treatment generally focuses on symptomatic relief, such as protecting the gastric mucosa and enhancing gastric motility. Additionally, traditional Chinese medicine has shown satisfactory effects in treating chronic atrophic gastritis. It is also important to maintain good dietary and living habits, prefer light and easily digestible foods, and avoid raw, greasy, spicy, and irritating foods to help maintain a positive state of mind. Regular gastroscopy check-ups are necessary. (Medication should be taken under the guidance of a doctor.)

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Written by Wu Hai Wu

Gastroenterology

44sec

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What are the symptoms before atrophic gastritis turns cancerous?

Patients with atrophic gastritis primarily exhibit symptoms such as dull pain, bloating, and burning pain in the upper abdomen, along with belching, acid reflux, weight loss, anemia, and more. If the pain from atrophic gastritis does not follow a clear pattern and is accompanied by progressive weight loss and refractory anemia, the possibility of cancerous changes in atrophic gastritis should be considered. It is advisable to promptly complete an endoscopy to confirm the diagnosis and rule out malignancy, and, if necessary, undertake a biopsy. In terms of treatment, it is first essential to test for Helicobacter pylori infection and then use medications to protect the gastric mucosa.

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Written by Wu Hai Wu

Gastroenterology

49sec

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Will atrophic gastritis and esophagitis cause significant weight loss?

Patients with atrophic gastritis and esophagitis may experience weight loss, as those with atrophic gastritis can have upper abdominal pain, distension pain, and burning pain, accompanied by a feeling of bloating and belching. Severe cases can lead to anemia and weight loss. The main cause of atrophic gastritis is infection by Helicobacter pylori. Of course, immune factors and dietary habits also play significant roles in the development of atrophic gastritis. Once atrophic gastritis is definitively diagnosed, it is crucial to actively eradicate Helicobacter pylori, as well as to quit smoking and drinking, and avoid using medications and consuming foods that may damage the gastric mucosa.

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Written by Si Li Li

Gastroenterology

1min 7sec

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Can atrophic gastritis eat rock candy?

Patients with atrophic gastritis should not eat rock sugar. The main symptoms of atrophic gastritis include upper abdominal distension and pain, belching, acid reflux, nausea, vomiting, poor appetite, and indigestion. A gastroscopy can reveal the atrophy of gastric mucosal glands, which can diagnose atrophic gastritis. The treatment primarily involves fighting Helicobacter pylori, suppressing acid and protecting the stomach, enhancing gastric motility, and repairing the gastric mucosa. Dietary considerations are crucial; one must quit smoking and drinking, avoid strong tea and coffee, and refrain from consuming spicy, fried, raw, cold, sweet foods, and barbecued items. Rock sugar, being a sweet food, must be strictly avoided as sweet foods can increase gastric acid secretion, leading to stomach mucosa irritation and worsening of the condition. Therefore, patients with atrophic gastritis should not consume rock sugar.

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Written by Xie Zheng Yuan

Gastroenterology

36sec

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How long does it take to treat atrophic gastritis with erosion?

Atrophic gastritis with erosion is a type of chronic gastritis and has a lengthy course of disease. Through treatment, the erosions may heal within six to eight weeks. However, reversing the atrophy of the gastric mucosa is a long-term and slow process, and there are no specific effective drugs clinically available. Some traditional Chinese medicines and proprietary Chinese medicines may be effective, but it typically takes at least six months. Therefore, the duration required to treat atrophic gastritis with erosion varies from person to person, depending on individual differences.