Kawasaki disease, once called mucocutaneous lymph node syndrome, is a disease of unknown cause and unclear pathogenesis. It is characterized by systemic vasculitis. Clinically, it mainly presents with fever, conjunctival congestion, cracked lips, congested oral mucosa, diffuse congestion, strawberry tongue, acute stage swelling and erythema of the hands and feet, polymorphous rash, and scarlet fever-like skin rash. It is often associated with unilateral or bilateral lymphadenopathy, which is not red on the surface, but the lymph nodes are hard and tender to the touch. It frequently involves complications such as myocarditis or pericarditis, with common coronary artery damage. The rash seen in Kawasaki disease is a manifestation of vasculitis and is generally non-itchy.