Does Kawasaki disease cause vomiting?

Written by Li Jiao Yan
Neonatology
Updated on September 03, 2024
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Kawasaki disease is a disease with no clear etiology, commonly seen in infants and toddlers, with eighty percent of cases occurring in children under five years old. Its main pathological change is systemic vasculitis. The main symptoms include fever, congested and cracked lips, diffuse congestion of the oral mucosa, swollen tongue papillae, and strawberry tongue. Other symptoms may include swelling of the hands and feet, polymorphous erythema, and enlarged lymph nodes. There could be subsequent cardiac complications, primarily affecting the coronary arteries. Kawasaki disease may cause vomiting due to the diffuse congestion in the oral cavity, and the pharynx might also be congested. When children experience significant congestion, their laryngeal reflex might be sensitive, possibly leading to vomiting. Furthermore, children with Kawasaki disease might develop secondary infections from other bacteria and viruses, which could also lead to symptoms like vomiting. Therefore, the manifestations of Kawasaki disease can vary, and if significant vomiting occurs, it should be investigated to determine the cause.

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Written by Li Jiao Yan
Neonatology
1min 18sec home-news-image

Does Kawasaki disease cause vomiting?

Kawasaki disease is a disease with no clear etiology, commonly seen in infants and toddlers, with eighty percent of cases occurring in children under five years old. Its main pathological change is systemic vasculitis. The main symptoms include fever, congested and cracked lips, diffuse congestion of the oral mucosa, swollen tongue papillae, and strawberry tongue. Other symptoms may include swelling of the hands and feet, polymorphous erythema, and enlarged lymph nodes. There could be subsequent cardiac complications, primarily affecting the coronary arteries. Kawasaki disease may cause vomiting due to the diffuse congestion in the oral cavity, and the pharynx might also be congested. When children experience significant congestion, their laryngeal reflex might be sensitive, possibly leading to vomiting. Furthermore, children with Kawasaki disease might develop secondary infections from other bacteria and viruses, which could also lead to symptoms like vomiting. Therefore, the manifestations of Kawasaki disease can vary, and if significant vomiting occurs, it should be investigated to determine the cause.

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Written by Shi Ji Peng
Pediatrics
54sec home-news-image

How is Kawasaki disease diagnosed?

Kawasaki disease, also known as mucocutaneous lymph node syndrome, is an acute febrile rash disease characterized primarily by inflammation of medium and small arteries throughout the body, with a self-limiting nature. Clinically, it mainly presents with fever, rash, mucosal lesions, conjunctival congestion, and non-suppurative enlargement of cervical lymph nodes. If untreated, 20% of cases can lead to coronary artery damage. To diagnose this disease, in addition to typical clinical manifestations, attention must also be paid to various tests such as blood tests, immunological tests, and ultrasound examinations for a comprehensive assessment. Although the clinical characteristics are largely indicative of the disease, ultrasound examination is crucial to check for any dilation of the coronary arteries.

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Written by Shi Ji Peng
Pediatrics
45sec home-news-image

How long does Kawasaki disease require hospitalization?

Kawasaki disease requires hospitalization and continued medication after discharge. The duration of the hospital stay is mainly determined by the child's clinical symptoms. The child can return home when the fever subsides and the dosage of aspirin is reduced, which may take about four to seven days, although this is just a general scenario. After discharge, medication must continue. If the child's coronary arteries are fine, with no dilation or lesions, a low dose of aspirin can be taken for about two months. If there are issues with the coronary arteries, aspirin must be continuously taken until the dilation resolves before stopping the aspirin, so this period can be quite long.

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Written by Yao Li Qin
Pediatrics
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What is Kawasaki disease? Is it contagious?

Kawasaki disease is a common pediatric febrile rash disease, also known as mucocutaneous lymph node syndrome. It is a systemic vasculitis syndrome mediated by immune mechanisms. Kawasaki disease may be caused by acute immune dysregulation due to infectious factors, and genetic factors may be related to the acute onset of the disease. Therefore, Kawasaki disease is not contagious, and contact with children with Kawasaki disease will not lead to transmission. Kawasaki disease generally occurs in infants and young children, and there is no clear seasonal pattern to its occurrence, nor significant gender differences.

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Written by Li Jiao Yan
Neonatology
48sec home-news-image

Is IgE high in Kawasaki disease?

Kawasaki disease, also known as mucocutaneous lymph node syndrome, has an unclear pathogenesis. It is speculated that certain components of infectious sources, such as superantigens, can activate CD30 T cells and CD40 ligand expression directly by binding with T cell antigen receptor fragments without going through mononuclear macrophages. Under the induction of carrier cells, there is polyclonal activation and reduced apoptosis of B08 cells, resulting in the production of large amounts of immunoglobulins such as IgG, IgM, IgA, and IgE, and cytokines. Therefore, the IgE levels in Kawasaki disease are elevated.