If rickets is not treated, what will be the impact?

Written by Mo Ming Hua
Pediatrics
Updated on November 09, 2024
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Rickets, if untreated, mainly involves changes in skeletal deformities and motor function in children. Rickets is primarily caused by a deficiency in vitamin D, which is essential for promoting the absorption of calcium. A deficiency in vitamin D leads to reduced calcium absorption. Lower calcium absorption results in a calcium deficiency in the body, which in turn causes changes in the bones. In the early stages of vitamin D deficiency, the main symptoms are increased neural excitability, which may manifest as startle reactions, irritability, restlessness, and excessive sweating. During the active phase, symptoms of increased nervous system excitability become more pronounced, mainly presenting as skeletal deformities. What aspects do these skeletal deformities affect? One is the softening of the skull, pigeon chest, funnel chest, and changes resembling wristbands and anklets. If the condition worsens further, it can present as X-shaped legs, O-shaped legs, and spinal deformities. Thus, if rickets progresses, it can lead to skeletal deformities and impairments in motor functions, among other issues.

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Written by Li Jiao Yan
Neonatology
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Early manifestations of rickets

Rickets is a disease caused by a lack of vitamin D, which leads to a disorder in calcium and phosphorus metabolism, resulting in abnormal bone development. It primarily appears in the early stages in infants within six months old, and particularly within three months after birth. The initial presentation is an increase in nervous excitability, such as fussiness and unease in children, symptoms like excessive internal heat and sweating, especially more sweat on the head. Continuous sweating can lead to significant baldness at the back of the head. Sometimes, children may exhibit constant head shaking, but these are not very specific symptoms. Early detection involves decreased blood calcium and phosphorus levels, increased parathyroid hormone levels, and decreased levels of related markers in blood tests. Early bone X-rays appear normal, so initial symptoms are not so typical. Therefore, it is recommended that infants be taken to a pediatrician for a physical examination as soon as possible, where their developmental status can be assessed and rickets can be diagnosed. If it is early-stage vitamin D deficiency rickets, timely supplementation of vitamin D levels can be an effective cure.

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Written by Li Jiao Yan
Neonatology
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Can rickets be inherited by the next generation?

Rickets, called vitamin D-deficiency rickets, is caused by a lack of vitamin D which leads to abnormal calcium and phosphorus metabolism in the body. This prevents calcium salts from properly depositing in the growing parts of the skeleton, resulting in incomplete mineralization of bone tissue during growth. It produces a systemic, chronic nutritional disease characterized by skeletal lesions and closely related to lifestyle. The primary causes of rickets are due to a combination of factors leading to vitamin D deficiency. Feeding methods, cod liver oil supplementation, living environment, time spent outdoors, recurrent respiratory infections, maternal calcium deficiency during pregnancy, and the season of birth are all significant contributing factors to the incidence of rickets. Generally, most cases of rickets are not inherited to the next generation. However, if there is a clear hereditary disease causing insufficient levels of vitamin D, it could potentially be inherited by the next generation.

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Written by Zhang Xian Hua
Pediatrics
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Is pillow baldness rickets?

Balding at the back of the head is a common clinical manifestation of rickets, but it does not mean that balding at the back of the head is equivalent to rickets, as there are many causes for this condition. In children with rickets, due to a lack of vitamin D leading to calcium deficiency, their neural excitability increases, which can affect the baby's sleep and cause restless sleep leading to balding at the back of the head. However, children who are in poor nutritional condition might also experience deficiencies in trace elements, such as a lack of zinc or iron, which can also lead to sleep disturbances and balding at the back of the head, indicating that the cause may not necessarily be rickets. Additionally, a small number of children might have an inherent condition of increased neural excitability that affects sleep, leading to balding at the back of the head, which also isn't due to rickets. Therefore, if balding at the back of the head occurs, it is advisable to visit a hospital’s pediatric healthcare department or pediatric outpatient clinic for a consultation and check-up, to actively treat and manage based on the underlying cause.

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Written by Li Jiao Yan
Neonatology
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Rickets is a disease characterized by the softening and weakening of bones in children, typically due to inadequate vitamin D.

Rickets is a disease, and its full name is Nutritional Vitamin D Deficiency Rickets. It is caused by a lack of vitamin D in children, leading to a disorder in calcium and phosphorus metabolism in the body. It is a chronic nutritional disease characterized by bone lesions. Its typical manifestation is incomplete mineralization of the growing long bone ends and bone tissue. The symptoms include abnormal development of the bones. Generally, without timely and effective intervention, it may lead to conditions such as pigeon chest, or S-shaped or O-shaped legs, which can seriously affect the child's life later on.

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Written by Yao Li Qin
Pediatrics
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Treatment of Rickets

Rickets is a nutritional metabolic disease caused by a lack of vitamin D, which also involves changes in the bones. Once rickets is definitively diagnosed, it is essential to start aggressive treatment. Treatment should be carried out under the guidance of a hospital doctor with high doses of vitamin D, while also appropriately supplementing the child with calcium. It's necessary to regularly draw blood to test for vitamin D levels and to monitor the improvement of various indicators in the child. When vitamin D levels have fully normalized, there will no longer be a need to administer high doses of vitamin D to the child, and the dosage can be adjusted to the physiological requirement. Additionally, it is crucial to increase the child’s outdoor activities and exposure to sunlight, as this is very helpful for the treatment and recovery of rickets. (For specific medication use, please follow the guidance of a doctor and do not self-medicate.)