Early symptoms of Parkinson's disease

Written by Liu Shi Xiang
Neurology
Updated on December 03, 2024
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The early symptoms of Parkinson's disease primarily include weakness of limbs on one side, resting tremors, and bradykinesia, among others. As the disease progresses, patients will display typical Parkinson's symptoms, including a shuffling gait, reduced facial expressions, decreased sense of smell, orthostatic hypotension, anxiety and depression, cognitive decline, constipation, frequent urination, etc. Therefore, when these symptoms appear, the possibility of Parkinson's disease should be considered. Patients need to promptly visit the neurology department of a hospital for complete testing such as routine blood tests, urinalysis, MRI of the skull, and if necessary, cerebrospinal fluid analysis through lumbar puncture to confirm the diagnosis. Once diagnosed, treatment with anti-Parkinson's medication should be started as soon as possible. Commonly used medications include Levodopa, dopamine receptor agonists, monoamine oxidase inhibitors, Vitamin B6, and more.

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Neurology
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Is Parkinson's disease dangerous?

Parkinson's disease is a chronic condition and a progressive degenerative disorder of the nervous system. The main symptoms include slowed movements, increased muscle tone, resting tremors, and abnormal posture and gait. The onset of the disease is slow and subtly worsens over time. Although not highly dangerous in itself and not directly life-threatening, Parkinson’s disease currently lacks a cure, and the condition gradually worsens. Generally, within about 10 to 20 years, patients may experience significant balance impairments. The main risks involve instability while walking, which can lead to falls and potentially cause fractures and other complications. In later stages, patients often become bedridden, leading to possible complications such as pulmonary infections, urinary tract infections, bedsores, and malnutrition. Therefore, Parkinson's disease is relatively mild, manageable in the early stages, but requires careful attention in later stages to prevent complications and avoid unnecessary harm.

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Is Parkinson's disease hereditary?

Parkinson's disease is mainly divided into two types. One type is familial Parkinson's disease, which definitely has a clear genetic predisposition. This disease is caused by mutations in some genes that lead to disruptions in some internal environments and the accumulation of abnormal proteins, eventually causing the death of neurons. Since the disease is caused by genetic mutations, there is definitely a certain genetic predisposition, and reproductive counseling is necessary to prevent the birth of offspring with Parkinson's disease. Moreover, most cases of Parkinson's disease are sporadic, and these diseases may be related to acquired factors, such as long-term mental stress, excessive pressure, brain trauma, or cerebrovascular diseases in patients, which can all lead to Parkinson's disease. This type of disease is definitely not inherited, so there is no need to worry too much.

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What department to see for Parkinson's disease?

Parkinson's disease is a very common degenerative neurological disorder in neurology, so if you go for treatment, you should definitely see a neurologist. Many neurologists have a high level of expertise in Parkinson's disease and have extensive experience in its diagnosis, differential diagnosis, and treatment. Patients with Parkinson's disease generally exhibit significant motor slowness, such as dressing, buttoning, wrapping dumplings, and eating very slowly, and they also walk very slowly. In addition, they may also display obvious resting tremors, muscle rigidity, general fatigue, unstable walking posture, and other clinical manifestations. Moreover, they might experience some constipation, anxiety, depression, and reduced sense of smell among other related clinical symptoms. Therefore, for this disease, visiting a neurologist is sufficient, and you can definitely expect a very satisfactory diagnosis and treatment.

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Neurology
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What are the symptoms of Parkinson's disease?

Parkinson's disease is a relatively common disease among the elderly, causing significant inconveniences in their daily lives and making it difficult for them to move. Moreover, this disease progressively worsens. Overall, the symptoms of Parkinson's disease primarily include noticeable movement slowness; patients perform tasks very slowly, such as wrapping dumplings or rolling dumpling wrappers, which are done clumsily and slowly. They also dress, turn over in bed, and tie shoelaces very slowly. Additionally, there are evident symptoms such as resting tremors and muscle rigidity. Some people may experience a panicked gait, rushing forward and unable to control their steps. Patients might also experience severe constipation, a reduced sense of smell, and some have sensory abnormalities in their limbs.

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How does one get Parkinson's disease?

Parkinson's disease is a degenerative disease of the nervous system. The actual mechanism of the disease is not very clear, and its fundamental cause has not yet been identified. It is generally believed that Parkinson's disease is mainly caused by the following factors. First, genetic factors. Some cases of Parkinson's disease have a clear familial tendency, where patients may experience mutations in synaptic nuclear protein genes, leading to abnormal aggregation of these proteins. This abnormal aggregation can damage the neurons in the substantia nigra of the midbrain, leading to Parkinson's disease. Second, there are some external factors related to sporadic cases of Parkinson's. These may be closely related to oxidative stress, trauma, poisoning, or an excessive stress response of the body. However, the specific cause is not very clear. Parkinson's disease, which causes symptoms such as bradykinesia, tremors, and rigidity, requires active treatment to improve the quality of life of the patients.