Early symptoms of Parkinson's disease

Written by Zhang Hui
Neurology
Updated on February 05, 2025
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Parkinson's disease in its early stages may primarily manifest as clumsiness in limb movement, especially in fine motor skills, such as difficulty in wrapping dumplings, rolling dumpling wrappers, or slow buttoning, which are clinical signs of early symptoms. Some patients may initially experience slight trembling in the limbs, which is generally more pronounced during rest and relaxation and diminishes during activity. Additionally, some individuals with early Parkinson's disease primarily exhibit non-motor symptoms, such as constipation, depression, reduced sense of smell, and may also experience rapid eye movement sleep behavior disorder, characterized by shouting and physical actions like punching or kicking during sleep.

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Written by Zhang Hui
Neurology
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What is needed to diagnose Parkinson's disease?

The definitive diagnosis of Parkinson's disease primarily relies on the patient's medical history, clinical manifestations, and a thorough physical examination by a neurologist. If the onset of the disease is very slow, presenting with symptoms such as bradykinesia and tremors, and the neurologist observes heightened muscle tone and slow movements during the examination, a high suspicion of this disease is warranted. Additionally, certain auxiliary tests are necessary, commonly including: First, testing the patient's sense of smell is crucial, as a reduced sense of smell is very important in diagnosing Parkinson's disease. Second, some brain MRI scans are needed mainly to exclude some secondary Parkinson's syndromes. Third, a brain PET-CT scan can be performed to examine the functionality of the striatum. Furthermore, an ultrasound of the substantia nigra in the midbrain can also be conducted, which holds significant value in assisting the diagnosis.

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Written by Zhang Hui
Neurology
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What are the symptoms of Parkinson's disease?

Parkinson's disease is a relatively common disease among the elderly, causing significant inconveniences in their daily lives and making it difficult for them to move. Moreover, this disease progressively worsens. Overall, the symptoms of Parkinson's disease primarily include noticeable movement slowness; patients perform tasks very slowly, such as wrapping dumplings or rolling dumpling wrappers, which are done clumsily and slowly. They also dress, turn over in bed, and tie shoelaces very slowly. Additionally, there are evident symptoms such as resting tremors and muscle rigidity. Some people may experience a panicked gait, rushing forward and unable to control their steps. Patients might also experience severe constipation, a reduced sense of smell, and some have sensory abnormalities in their limbs.

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Written by Zhou Yan
Geriatrics
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Initial symptoms of Parkinson's disease

The early symptoms of Parkinson's disease are divided into motor symptoms and non-motor symptoms. The onset of Parkinson's disease is relatively concealed and progresses gradually. The initial symptoms can be tremors, bradykinesia, or rigidity, occurring asymmetrically. It often starts in one upper limb and can initially appear in the lower limbs in a few cases, gradually extending to the limbs on the other side. Non-motor symptoms can occur at any stage of Parkinson's disease, including before motor symptoms arise, such as loss of smell, rapid eye movement sleep behavior disorder, constipation, and depression. These are often precursory symptoms of Parkinson’s disease, but such non-motor symptoms can also appear in other diseases, which can make them difficult to clearly distinguish.

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Written by Zhou Yan
Geriatrics
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Early symptoms of Parkinson's disease

Parkinson's disease begins inconspicuously and progresses gradually. There are two main categories of symptoms in Parkinson's disease: motor symptoms and non-motor symptoms. In the early stages of the disease, one can appear normal, or may experience motor symptoms like bradykinesia or rigidity, often starting asymmetrically. Symptoms commonly begin on one side of the upper limbs, and less frequently start from the lower limbs, eventually spreading to the limbs on the other side. Non-motor symptoms can occur at various stages of Parkinson's disease, including the pre-motor phase, such as loss of smell, sleep disturbances, constipation, depression, and more.

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Written by Zhang Hui
Neurology
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What is good to eat for Parkinson's disease?

Patients with Parkinson's disease should pay special attention to their diet. It is recommended that the food eaten by Parkinson's patients mainly includes the following types: First, patients can eat more fresh cabbage, vegetables, celery, and fruits such as apples, oranges, bananas, and tangerines, because these fruits and vegetables help supplement some vitamins. Vitamins have an antioxidant stress effect, which may play a role in preventing the further development of Parkinson's disease. Additionally, these foods can supplement water, promote gastrointestinal motility, and alleviate constipation, which is beneficial for the constipation caused by Parkinson's disease. Second, people with Parkinson's disease can eat more walnuts or black sesame seeds, as well as some other nuts, as these foods also nourish brain cells. Moreover, patients with Parkinson's disease must ensure a balanced diet that includes a variety of grains, such as rice, millet, corn, and sorghum, which are all consumable.