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Parkinson's disease
How does one get Parkinson's disease?
Parkinson's disease is a degenerative disease of the nervous system. The actual mechanism of the disease is not very clear, and its fundamental cause has not yet been identified. It is generally believed that Parkinson's disease is mainly caused by the following factors. First, genetic factors. Some cases of Parkinson's disease have a clear familial tendency, where patients may experience mutations in synaptic nuclear protein genes, leading to abnormal aggregation of these proteins. This abnormal aggregation can damage the neurons in the substantia nigra of the midbrain, leading to Parkinson's disease. Second, there are some external factors related to sporadic cases of Parkinson's. These may be closely related to oxidative stress, trauma, poisoning, or an excessive stress response of the body. However, the specific cause is not very clear. Parkinson's disease, which causes symptoms such as bradykinesia, tremors, and rigidity, requires active treatment to improve the quality of life of the patients.
Is Parkinson's disease hereditary?
Parkinson's disease is mainly divided into two types. One type is familial Parkinson's disease, which definitely has a clear genetic predisposition. This disease is caused by mutations in some genes that lead to disruptions in some internal environments and the accumulation of abnormal proteins, eventually causing the death of neurons. Since the disease is caused by genetic mutations, there is definitely a certain genetic predisposition, and reproductive counseling is necessary to prevent the birth of offspring with Parkinson's disease. Moreover, most cases of Parkinson's disease are sporadic, and these diseases may be related to acquired factors, such as long-term mental stress, excessive pressure, brain trauma, or cerebrovascular diseases in patients, which can all lead to Parkinson's disease. This type of disease is definitely not inherited, so there is no need to worry too much.
How is Parkinson's disease cured?
The treatment of Parkinson's disease involves various aspects, and the principle of its treatment is not to aim for complete effectiveness but for prolonged and sustainable management. It is important not to be tempted by temporary symptom improvement and miss out on a sequential treatment that could last for many years. The treatment of Parkinson’s disease mainly includes the following aspects: The first aspect is the care of daily life, which is very important. It is necessary to install some very convenient facilities at home for the patient, such as installing some handles, using some higher chairs, etc., all of which help to improve the quality of life for the patient. The second aspect is pharmacotherapy. According to the patient's condition, appropriate anti-Parkinson's medication is selected, mainly including dopamine receptor agonists, COMT inhibitors, and some levodopa preparations. Adjusting medication is very complex and must be conducted under the guidance of a professional neurologist. In addition, attention should also be paid to the treatment of non-motor symptoms, such as treating the patient's constipation, depression, etc.