How is Parkinson's disease cured?

Written by Zhang Hui
Neurology
Updated on September 02, 2024
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The treatment of Parkinson's disease involves various aspects, and the principle of its treatment is not to aim for complete effectiveness but for prolonged and sustainable management. It is important not to be tempted by temporary symptom improvement and miss out on a sequential treatment that could last for many years. The treatment of Parkinson’s disease mainly includes the following aspects:

The first aspect is the care of daily life, which is very important. It is necessary to install some very convenient facilities at home for the patient, such as installing some handles, using some higher chairs, etc., all of which help to improve the quality of life for the patient.

The second aspect is pharmacotherapy. According to the patient's condition, appropriate anti-Parkinson's medication is selected, mainly including dopamine receptor agonists, COMT inhibitors, and some levodopa preparations. Adjusting medication is very complex and must be conducted under the guidance of a professional neurologist.

In addition, attention should also be paid to the treatment of non-motor symptoms, such as treating the patient's constipation, depression, etc.

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Written by Zhang Hui
Neurology
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What is Parkinson's disease gait?

Patients with Parkinson's disease have a distinctive gait; typically, their torso leans forward, and their arms do not move much. When they walk, they exhibit a hurried gait with short, scurrying steps. That is, they take small steps that progressively get faster and faster, making stopping very difficult when they reach their destination. This is a typical scenario often referred to as a "scampering gait." Many experienced doctors can frame a preliminary diagnosis of Parkinson's disease just by observing the patient’s walk. Parkinson's disease also leads to unstable posture and gait, increasing the risk of falls and fractures. Therefore, it's important to take precautions at home by installing handrails to assist the patient in standing and walking, preventing accidental injuries.

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Written by Zhou Yan
Geriatrics
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How long does the course of Parkinson's disease usually last?

The course of Parkinson's disease generally lasts for how long? Parkinson's disease, also known as shaking palsy, is a common neurodegenerative disease, and the age at onset varies. For early-onset Parkinson's disease, it generally starts around age 40 to 50, while late-onset Parkinson's disease generally starts after age 50. As age gradually increases, the course of Parkinson's disease is generally about 20 to 40 years. Once diagnosed with Parkinson's disease, it is a lifelong condition. This disease is incurable, and can only be managed through medications, surgical treatments, physical rehabilitation, and psychological therapies to improve or control symptoms, but it cannot be cured. Therefore, once diagnosed with Parkinson's disease, the disease is lifelong.

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Written by Zhou Yan
Geriatrics
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What are the symptoms of Parkinson's disease?

The main symptoms of Parkinson's disease are divided into two major categories: motor symptoms and non-motor symptoms. The motor symptoms include bradykinesia and hypokinesia, specifically characterized by slow movement speed and reduced amplitude. In daily life, this results in clumsiness with actions such as difficulty standing up, small arm swings while walking, or even no swinging at all, a lack of facial expressions, and progressively smaller handwriting. The second type is resting tremor, which includes pill-rolling movements along with muscle rigidity and postural and gait imbalances, such as a panicked gait or taking very small steps that accelerate and become faster without the ability to stop or turn promptly. Non-motor symptoms include issues such as olfactory dysfunction, sleep disturbances, constipation, and depression.

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Written by Zhou Yan
Geriatrics
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Can Parkinson's disease be cured?

The core treatment for Parkinson's disease currently is pharmacotherapy, with surgical treatment serving as a supplement. Additionally, physical rehabilitation and psychological therapy are also recommended. The most effective drugs against Parkinson's at present include Levodopa, or compound Levodopa preparations. Other treatments include dopamine receptor agonists, monoamine oxidase inhibitors, amantadine, anticholinergic drugs, and catechol-O-methyl transferase inhibitors. Furthermore, there are treatments aimed at non-motor symptoms, such as psychiatric symptoms, cognitive impairments, autonomic dysfunctions, and sleep disorders. For drug treatments, it is advisable to start with a low dose and gradually increase to an appropriate dosage while maintaining the medication regimen. Currently, we cannot cure Parkinson's disease; we can only provide relief to the symptoms and slow the progression of the disease through comprehensive treatment. (The use of medications should be under the guidance of a doctor.)

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Written by Zhang Hui
Neurology
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What are the symptoms of Parkinson's disease?

Parkinson's disease is a relatively common disease among the elderly, causing significant inconveniences in their daily lives and making it difficult for them to move. Moreover, this disease progressively worsens. Overall, the symptoms of Parkinson's disease primarily include noticeable movement slowness; patients perform tasks very slowly, such as wrapping dumplings or rolling dumpling wrappers, which are done clumsily and slowly. They also dress, turn over in bed, and tie shoelaces very slowly. Additionally, there are evident symptoms such as resting tremors and muscle rigidity. Some people may experience a panicked gait, rushing forward and unable to control their steps. Patients might also experience severe constipation, a reduced sense of smell, and some have sensory abnormalities in their limbs.