Cirrhosis

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Written by Yang Chun Guang
Gastroenterology
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Can alcoholic cirrhosis be contagious?

Cirrhosis caused by hepatitis formed by alcohol is not contagious in clinical settings. Contagious cirrhosis generally refers to viral hepatitis, such as hepatitis A, B, C, and E, which are infectious. Alcoholic cirrhosis, primarily caused by drinking, is not caused by viruses; hence, alcohol does not facilitate transmission between people. The common transmission modes involve fecal-oral routes, for instance, through blood and bodily fluids in hepatitis A and B. In contrast, alcoholic liver disease is relatively safe, so there is no need to worry about it being contagious.

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Written by Zhang Jian Kang
Infectious Disease
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Symptoms of decompensated cirrhosis due to hepatitis B

Hepatitis B virus infection repeatedly leads to severe damage to the liver. If chronic hepatitis is not actively controlled, cirrhosis may occur. A symptom of decompensated cirrhosis mainly manifests as ascites, gastrointestinal bleeding, portal hypertension, and some people exhibit symptoms of hepatic encephalopathy. The presence of these complications indicates that the patient has reached the stage of decompensated cirrhosis. Patients in this stage often exhibit distinct jaundice, dark urine, abdominal distension after eating, and the presence of ascites with a positive shifting dullness. Additionally, some patients may experience vomiting blood, black stools, liver coma, and other related symptoms. Once these symptoms appear, it indicates that the prognosis for the patient is relatively poor.

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Written by Zhang Jian Kang
Infectious Disease
1min 8sec home-news-image

Is hepatitis B cirrhosis contagious?

If hepatitis B is not well controlled, it can easily lead to the occurrence of cirrhosis. After the hepatitis B virus infects the human body, it causes repeated inflammatory damage to the liver, with recurring abnormalities in liver function. If during this period there is no formal antiviral treatment or lack of attention, it is very likely to lead to the development of cirrhosis. Once cirrhosis from hepatitis B occurs, it is generally irreversible. Cirrhosis due to hepatitis B is also an infectious disease, and its level of infectiousness mainly depends on the presence of the virus. If the viral load is positive, indicated by a positive HBV-DNA test, then it is infectious. If HBV-DNA is negative, then it is not infectious. Therefore, whether cirrhosis from hepatitis B is infectious primarily depends on the level of HBV-DNA.

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Written by Huang Ya Juan
Gastroenterology
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Early symptoms of cirrhosis

Liver cirrhosis is generally divided into compensated and decompensated stages: The compensated stage is actually an early stage of liver cirrhosis. During this stage, most patients do not show symptoms, or they may experience some mild symptoms such as abdominal discomfort, fatigue, loss of appetite, abdominal bloating, indigestion, diarrhea, etc. Decompensated stage: Early stages often present with fatigue and weakness, and later stages can include weight loss, loss of appetite, aversion to oily foods, abdominal bloating, diarrhea, fever, etc.; The liver is the only site of albumin synthesis, and during cirrhosis, reduced serum albumin can cause edema and ascites; the liver synthesizes most clotting factors, and cirrhosis can lead to coagulation disorders, clinically manifesting as gum bleeding, skin bruising, and nosebleeds; During cirrhosis, there can also be metabolic disorders of bilirubin and bile acids, leading to jaundice; Cirrhosis can also cause hormonal metabolic abnormalities, especially in patients with alcoholic cirrhosis, who may exhibit many characteristics of male dysfunction, including impotence, erectile dysfunction, testicular atrophy, loss of body hair and muscle mass, feminization, etc. Female patients may experience cessation or reduction of menstruation, excessive menstruation, infertility, etc.; Both male and female patients can develop osteoporosis, leading to spontaneous fractures.

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Written by Yang Chun Guang
Gastroenterology
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Is liver cirrhosis with ascites contagious?

Liver cirrhosis in the decompensated stage with ascites present is not inherently contagious. Whether the condition is infectious depends not on the severity of liver function, the degree of liver cirrhosis, or the gravity of ascites, but rather on the underlying cause of the liver cirrhosis. For example, liver cirrhosis caused by alcohol consumption is not contagious. However, if the liver cirrhosis is due to viral hepatitis, such as commonly seen with hepatitis B or C, the condition can be infectious. Therefore, the presence of ascites or liver cirrhosis itself is not an indicator of infectiousness; the crucial factor is whether there is an infectious virus present.

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Written by Yang Chun Guang
Gastroenterology
56sec home-news-image

How to treat splenomegaly and liver cirrhosis?

Once liver cirrhosis is detected, accompanied by an enlarged spleen and hyperactive spleen function, this condition can be addressed through interventional methods to resolve issues of spleen enlargement and hyperfunction. This reduces the destruction of red blood cells, white blood cells, and platelets. The interventional approach primarily involves sterile necrosis and absorption of the spleen, thus resolving spleen issues. As for treating liver cirrhosis, it is primarily important to understand the causes of the cirrhosis. If the cirrhosis is caused by a virus, antiviral treatment is needed. There are corresponding antiviral medications for cirrhosis caused by hepatitis B and C. If the cirrhosis is caused by alcohol, it is essential to abstain from alcohol as part of the treatment. In addition, medications that combat liver cirrhosis should be used.

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Written by Shen Jiang Chao
Radiology
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Can liver cirrhosis be detected by an ultrasound B-scan?

Liver cirrhosis can be diagnosed with an ultrasound. In the early stages of cirrhosis, there are no specific changes in the sonographic pattern visible on ultrasound. Typically, cirrhosis manifests as a decrease in liver volume, with imbalanced proportions of the liver lobes; both the left and right lobes may shrink, with compensatory hypertrophy observed in some cases in the left lobe. The liver capsule appears serrated, and the echoes from the liver area are coarser and stronger, with uneven distribution. It's possible to observe nodules with low or high echoes. The liver vessels vary in thickness, the hepatic veins may narrow, and the portal vein can widen. An enlarged portal vein can lead to symptoms like splenomegaly and ascites.

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Written by Shen Jiang Chao
Radiology
48sec home-news-image

Can cirrhosis be detected by a CT scan?

Cirrhosis can be detected by a CT scan. Early-stage cirrhosis has no specific diagnostic value on CT, but middle to late-stage cirrhosis typically manifests as wavy changes in the liver capsule, enlarged liver lobes, and disproportionate size of liver lobes, with most changes involving an enlargement of the left lobe and caudate lobe and a relative shrinkage of the right lobe. Additionally, secondary manifestations of cirrhosis, such as portal hypertension, can cause enlargement of the spleen and varices in the lower esophagus and stomach fundus. When cirrhosis is detected, it is advisable to perform an enhanced CT scan to determine the potential for malignant transformation in liver regenerative nodules.