Cirrhosis

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Written by Yuan Lin Yan
Infectious Disease
1min 12sec home-news-image

Is hepatitis B with liver cirrhosis severe?

Hepatitis B-related cirrhosis is a form of liver cirrhosis caused by the hepatitis B virus, and it is more severe than chronic hepatitis B. However, cirrhosis can be categorized into compensated cirrhosis and decompensated cirrhosis. Decompensated cirrhosis refers to the advanced stages of cirrhosis, characterized by significant hardening of the liver, and complications such as ascites, hepatic encephalopathy, and gastrointestinal bleeding may occur. This type of cirrhosis is severe and has a high mortality rate, and even timely antiviral therapy against hepatitis B cannot effectively delay the progression of the disease. Compensated cirrhosis refers to the early stages of cirrhosis, where complications like ascites, hepatic encephalopathy, and gastrointestinal bleeding are not present, making this type of cirrhosis comparatively less severe. With timely antiviral therapy against hepatitis B, the progression of cirrhosis can be delayed.

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Written by Ye Xi Yong
Infectious Diseases
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Can cirrhosis caused by hepatitis B virus be cured?

Hepatitis B virus-induced cirrhosis was previously considered incurable, though its progression could be slowed. However, recent observations and studies have shown that a small fraction of patients with early-stage hepatitis B virus-induced cirrhosis can be cured. However, the proportion of these patients is extremely low. To draw an analogy, cirrhosis is like our houses. If the cement, steel bars, and brick structure are damaged, then the house is difficult to repair. Cirrhosis is akin to the structural damage of the house, making it hard to recover.

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Written by Huang Gang
Gastroenterology
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The difference between fatty liver and liver cirrhosis

Fatty liver is shown through ultrasound as having an increased and finely detailed echo in the liver, which is completely different from liver cirrhosis. Liver cirrhosis is generally caused by the progression of chronic hepatitis, commonly seen in hepatitis B-related cirrhosis, hepatitis C-related cirrhosis, and alcoholic cirrhosis. Cirrhosis resulting from drug-induced liver damage or from severe fatty liver is relatively rare in clinical practice. Therefore, we should not panic. Once diagnosed with fatty liver, it can be reversed through proper diet and reasonable exercise, and its progression to liver cirrhosis can be prevented. So, everyone, there is no need to rush or panic.

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Written by Zhang Jian Kang
Infectious Disease
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Can you have intercourse after hepatic cirrhosis caused by hepatitis B?

Liver cirrhosis caused by hepatitis B, if not treated with standard antiviral therapy, is very likely to test positive for the hepatitis B virus. HBV-DNA is a good indicator of the hepatitis B virus; if HBV-DNA tests positive, then it is contagious. The main transmission routes of hepatitis B include mother-to-child transmission, blood and body fluid transmission, and sexual transmission between spouses, though this route carries a relatively lower risk. Why is this the case? Firstly, the spouse may already have hepatitis B surface antibodies, which are protective antibodies providing immunity against hepatitis B. Secondly, when adults are infected with hepatitis B, most can acutely clear the virus, preventing the chronic manifestation of the disease.

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Written by Yang Chun Guang
Gastroenterology
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Is alcoholic cirrhosis ascites serious?

Once ascites caused by alcoholic liver cirrhosis is discovered, it indicates that the liver has reached the decompensated stage of cirrhosis, which is quite severe. Decompensated cirrhosis itself has a relatively low five-year and ten-year survival rate. Moreover, once the liver enters the decompensated stage, it is also prone to corresponding complications, such as gastrointestinal bleeding, hepatic encephalopathy, infections, etc. Therefore, when alcoholic liver cirrhosis presents with ascites, it is crucial to seek treatment at a formal hospital. The condition is quite serious and requires active treatment.

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Written by Ye Xi Yong
Infectious Diseases
1min 9sec home-news-image

How long can one live with hepatitis B-related cirrhosis?

We cannot give a definite answer on how long a patient with hepatitis B-related cirrhosis can live, as the life expectancy in late-stage cirrhosis is influenced by many factors including treatment measures, lifestyle adjustments, daily healthcare, and physical condition. Patients in the compensated stage of cirrhosis, if treated and the progression of cirrhosis is halted, with normal liver function and negative hepatitis B virus replication indicators, can work normally. In this state, the quality of life is good, and they can live to 70 to 80 years old. For patients in the decompensated stage of cirrhosis, if untreated and the cirrhosis is allowed to progress, about 70 to 80% may die within 5 years; however, aggressive treatment, including traditional Chinese medicine for liver fibrosis and cirrhosis, combined with antiviral treatment, bleeding prevention, liver protection, and liver transplantation, can significantly increase the survival time of patients.

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Written by Li Hu Chen
Imaging Center
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Can cirrhosis be detected by ultrasound B?

If there are signs of hardening in the liver, which we call cirrhosis, an ultrasound, specifically a hepatobiliary ultrasound, can detect it. Especially in the middle and late stages, cirrhosis has some characteristic features on an ultrasound. First, one can observe the size of the liver. By the middle and late stages, the liver usually shrinks—a slight enlargement may occur early on, but it generally progressively diminishes. Additionally, the texture of the liver becomes harder, and through the ultrasound, the texture appears uneven with a bumpy feeling, or in other words, there can be seen a diffuse and uneven echo. However, for early-stage cirrhosis, a standard ultrasound may not be as sensitive. Nowadays, there are digital liver ultrasounds specifically designed to measure the degree of liver hardness, which provide objective data to help diagnose more sensitively and objectively. This method can definitely detect the condition.

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Written by Zhang Jian Kang
Infectious Disease
1min 9sec home-news-image

Is hepatitis B cirrhosis serious?

After infection with the hepatitis B virus, it may cause repeated inflammatory damage to the liver. If hepatitis B is not well-controlled, it can lead to the development of liver cirrhosis. The symptoms of liver cirrhosis mainly manifest as repeated fatigue, poor appetite, yellowing of the eyes, yellow urine, and discomfort in the upper abdomen after eating, etc. If the cirrhosis due to hepatitis B is in a compensated stage, such as liver cirrhosis suggested by ultrasonography and mild abnormalities in liver function, and the symptoms are not very severe, this type of compensatory cirrhosis, relatively speaking, has a decent prognosis. With standard antiviral treatment, many patients can maintain a state of liver cirrhosis. However, if treatment is not further pursued and damage progresses, leading to decompensated liver cirrhosis, or if ascites has already developed, or even gastrointestinal bleeding occurs, then its prognosis is relatively poor, and this situation is very serious.

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Written by Huang Gang
Gastroenterology
1min 2sec home-news-image

How long does it take for fatty liver to progress to cirrhosis?

How long does it take for fatty liver to progress to cirrhosis? Fatty liver is generally divided into mild, moderate, and severe fatty liver. If it is mild or moderate fatty liver, it can be reversed through proper exercise and diet control, meaning it can be cured. However, once it progresses to severe fatty liver, it can easily develop into cirrhosis, but the specific time required is about five years. Therefore, once we have fatty liver, it must be taken very seriously. With the improvement of living standards, most people are obese, which means that fatty liver is mostly caused by obesity. In terms of treatment, the focus is mainly on the cause, which is obesity. Patients need to follow a reasonable diet and actively exercise to lose weight. If successful in losing weight, fatty liver can be reversed, and we do not have to worry about fatty liver developing into cirrhosis.

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Written by Wang Ji Zhong
Internal Medicine
1min 11sec home-news-image

Symptoms of alcoholic liver cirrhosis

Long-term alcohol consumption can lead to alcoholic liver disease, with alcoholic liver cirrhosis being one of its main manifestations. Initially, it presents with reduced liver function, symptoms such as loss of appetite, abdominal pain, bloating, vomiting, aversion to oily foods, diarrhea, and nausea, which are indicative of hepatitis. Additionally, there may be darkening of the skin, menstrual irregularities, and even signs like liver palms and spider angiomas due to metabolic disorders. Furthermore, disruptions in carbohydrate metabolism can lead to nutritional excess, increasing lipid levels in the body and leading to fatty liver and hyperlipidemia. There can also be abnormal protein synthesis, resulting in ascites, pleural effusion, and other symptoms of liver dysfunction. Additionally, abnormalities in vitamin metabolism can cause rough skin and edema. Coagulation factors are often abnormal as well, leading to symptoms such as bleeding gums and nosebleeds. Therefore, it is crucial to seek medical attention promptly in these situations to restore normal health.